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研究和临床试验中的种族和民族差异。

Racial and Ethnic Disparities in Research and Clinical Trials.

机构信息

Department of Dermatology, Keck School of Medicine, University of Southern California, 830 South Flower Street, Ste 100, Los Angeles, CA 90017, USA.

Department of Dermatology, Keck School of Medicine, University of Southern California, 830 South Flower Street, Ste 100, Los Angeles, CA 90017, USA.

出版信息

Dermatol Clin. 2023 Apr;41(2):351-358. doi: 10.1016/j.det.2022.10.007. Epub 2023 Feb 1.

Abstract

Clinical trials are an essential component of research for determining the safety and efficacy of treatments for medical diseases. In order for the results of clinical trials to be generalizable to diverse populations, they must include participants at ratios that are reflective of national and global populations. A significant number of dermatology studies not only lack racial/ethnic diversity but also fail to report data on minority recruitment and enrollment. Reasons for this are multifold and are discussed in this review. Although steps have been implemented to improve this issue, greater efforts are needed for sustained and meaningful change.

摘要

临床试验是确定医学疾病治疗安全性和有效性的研究的重要组成部分。为了使临床试验结果能够推广到不同人群,它们必须包括与国家和全球人口比例相符的参与者。相当数量的皮肤病学研究不仅缺乏种族/民族多样性,而且未能报告少数民族招募和入学的数据。造成这种情况的原因有很多,本文对此进行了讨论。尽管已经采取了措施来改善这一问题,但仍需要更大的努力才能实现持续和有意义的变革。

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