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在 COVID-19 大流行期间,抑郁和创伤后应激障碍的症状和风险因素:2020 年至 2022 年在日本进行的纵向调查。

Symptoms and risk factors of depression and PTSD in the prolonged COVID-19 pandemic: a longitudinal survey conducted from 2020 to 2022 in Japan.

机构信息

Kitasato University School of Allied Health Sciences, Kitazato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan.

出版信息

BMC Psychiatry. 2023 Mar 20;23(1):180. doi: 10.1186/s12888-023-04670-7.

Abstract

BACKGROUND

The present study aimed to explore changes in depression and posttraumatic stress disorder (PTSD) among the general population during the prolonged COVID-19 pandemic and to investigate risk factors and adaptive/nonadaptive strategies.

METHODS

A web-based longitudinal survey was conducted across five timepoints from 2020 to 2022 in Japan. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9), PTSD was measured using Impact of Event Scale-Revised (IESR), and coping strategies were measured using Brief Coping Orientation to Problems Experienced (Brief COPE). Higher scores of PHQ-9 and IESR indicate more symptoms and Higher score of Brief COPE indicate that these means of coping are used very frequently.

RESULTS

A total of 1,366 participants (mean age = 52.76, SD = 15.57) were analyzed. Regarding levels of depression, PHQ-9 scores in 2022 were lower than in 2020 and 2021 (all p < 0.01). Regarding levels of PTSD, IESR scores in 2022 were lower than in 2021 among females (p < 0.001). Being younger (β = -0.08 and - 0.13, both p < 0.01) and engaging in self-blame (β = 0.12 and 0.18, both p < 0.01) increased PHQ-9 scores regardless of sex. For males, not working (β = 0.09, p = 0.004) and having suffered an economic impact (β = 0.07, p = 0.003) were risk factors for depressive symptoms, and active coping (β = -0.10, p = 0.005) was associated with decreased depressive symptoms. For females, substance use (β = 0.07, p = 0.032) and behavioral disengagement (β = 0.10, p = 0.006) increased depressive symptoms, and females did not show strategies that decreased the symptoms.

CONCLUSIONS

Levels of depression might have increased in the early stages of the pandemic and decreased in January 2022. Although males need to improve their economic situation to decrease depressive symptoms, adaptive strategies might be difficult to identify due to the prolonged pandemic among both sexes. In addition, the pandemic might be a depressive event but not a traumatic event among the general population, at least in Japan.

摘要

背景

本研究旨在探讨在 COVID-19 大流行期间,普通人群中抑郁和创伤后应激障碍(PTSD)的变化,并探讨风险因素和适应性/非适应性应对策略。

方法

本研究采用在线纵向调查,于 2020 年至 2022 年在日本进行了五个时间点的调查。使用患者健康问卷-9(PHQ-9)测量抑郁症状,使用修订后的事件影响量表(IESR)测量 PTSD,使用Brief Coping Orientation to Problems Experienced(Brief COPE)测量应对策略。PHQ-9 和 IESR 的得分越高表示症状越严重,Brief COPE 的得分越高表示这些应对方式使用得越频繁。

结果

共分析了 1366 名参与者(平均年龄 52.76,标准差 15.57)。关于抑郁水平,2022 年的 PHQ-9 得分低于 2020 年和 2021 年(均 p<0.01)。关于 PTSD 水平,女性 2022 年的 IESR 得分低于 2021 年(p<0.001)。年轻(β=-0.08 和-0.13,均 p<0.01)和自责(β=0.12 和 0.18,均 p<0.01)增加 PHQ-9 评分与性别无关。对于男性,不工作(β=0.09,p=0.004)和遭受经济影响(β=0.07,p=0.003)是抑郁症状的危险因素,而积极应对(β=-0.10,p=0.005)与抑郁症状减轻有关。对于女性,物质使用(β=0.07,p=0.032)和行为脱离(β=0.10,p=0.006)增加了抑郁症状,而女性没有表现出减轻症状的策略。

结论

抑郁水平可能在大流行早期有所增加,而在 2022 年 1 月有所下降。虽然男性需要改善经济状况以减轻抑郁症状,但由于男女双方大流行的持续,适应性策略可能难以确定。此外,大流行在日本至少是普通人群中的一个抑郁事件,但不是创伤事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9846/10026456/f4e64ba9f15c/12888_2023_4670_Figa_HTML.jpg

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