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未计划妊娠对新生儿结局的影响:秘鲁高危新生儿的新发现。

Impact of unplanned pregnancy on neonatal outcomes: findings of new high-risk newborns in Peru.

机构信息

Universid ad Privada de Tacna, Faculty of Health Sciences, 23003, Tacna, Peru.

Universidad Nacional Jorge Basadre Grohmann, Faculty of Health Sciences, 23003, Tacna, Peru.

出版信息

Int Health. 2024 Jan 2;16(1):52-60. doi: 10.1093/inthealth/ihad018.

Abstract

BACKGROUND

Unplanned pregnancy is a significant public health problem, especially in low- to middle-income countries. The objective of this study was to determine the neonatal outcomes associated with unplanned pregnancy in a public hospital in southern Peru.

METHODS

A cross-sectional analytical study was conducted from June to August 2021 among 306 mothers and their newborns selected by convenience sampling. After obtaining informed consent, mothers were surveyed during their postpartum hospitalization about their pregnancy intentions. Unintended pregnancy was considered when it was mistimed or unwanted. Neonatal outcomes were assessed by reviewing medical records prior to discharge, evaluating the presence of low birth weight, insufficient birth weight, prematurity, respiratory distress syndrome, sepsis and neonatal mortality. Association was measured in terms of prevalence ratio (PR) and beta coefficient and respective 95% CIs, crude and adjusted for variables that obtained a value of p<0.20 in the crude model (maternal age, education and parity).

RESULTS

The overall unplanned pregnancies rate was 65%, of which 40.5% were mistimed pregnancies and 24.5% unwanted pregnancies. Unplanned and mistimed pregnancies were significantly associated with insufficient birth weight [adjusted prevalence ratio (aPR)=2.14; 95% CI 1.01 to 4.56 and aPR=2.43; 95% CI 1.09 to 5.39, respectively] and unwanted pregnancies were significantly associated with preterm birth (aPR=3.49; 95% CI 1.01 to 12.11). Furthermore, adjusted analysis showed that birth weight and gestational age were lower in unplanned, mistimed and unwanted pregnancies.

CONCLUSIONS

Unplanned pregnancy was associated with lower birth weight and shorter gestational age of newborns. These data collected in a public hospital in a developing country may have significant implications today. If pregnancy intention is not included as a neonatal risk factor, insufficient birth weight and preterm birth could increase because a higher proportion of births will be unplanned.

摘要

背景

意外妊娠是一个重大的公共卫生问题,尤其是在中低收入国家。本研究旨在确定秘鲁南部一家公立医院中与意外妊娠相关的新生儿结局。

方法

这是一项于 2021 年 6 月至 8 月期间进行的横断面分析性研究,通过便利抽样选择了 306 名母亲及其新生儿。在获得知情同意后,母亲们在产后住院期间接受了关于妊娠意图的调查。意外妊娠被定义为时机不当或不想要的妊娠。新生儿结局通过出院前查阅病历进行评估,评估低出生体重、出生体重不足、早产、呼吸窘迫综合征、败血症和新生儿死亡的发生情况。使用患病率比(PR)和β系数及其相应的 95%置信区间(CI)来衡量关联,采用粗模型中 p<0.20 的变量进行调整(母亲年龄、教育程度和产次)。

结果

总的意外妊娠率为 65%,其中 40.5%为时机不当妊娠,24.5%为不想要的妊娠。意外妊娠和时机不当妊娠与出生体重不足显著相关(调整后的患病率比[aPR]=2.14;95%CI 1.01 至 4.56 和 aPR=2.43;95%CI 1.09 至 5.39),不想要的妊娠与早产显著相关(aPR=3.49;95%CI 1.01 至 12.11)。此外,调整分析显示,意外妊娠、时机不当妊娠和不想要妊娠的新生儿出生体重和胎龄较低。

结论

意外妊娠与新生儿出生体重较低和胎龄较短相关。这些在发展中国家的公立医院中收集的数据可能具有重要意义。如果不将妊娠意图纳入新生儿风险因素,出生体重不足和早产的比例可能会增加,因为更多的分娩将是意外妊娠。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63cd/10759294/37877a6df02b/ihad018fig1.jpg

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