MYBPC3 截断突变的杂合不足是否为充分机制？
Is haploinsufficiency a sufficient mechanism for MYBPC3 truncating mutations?
机构信息
Department of Cell and Molecular Physiology, Loyola University Chicago , Maywood, IL, USA.
出版信息
J Gen Physiol. 2023 Apr 3;155(4). doi: 10.1085/jgp.202313351. Epub 2023 Mar 22.
Abstract
Reduced expression of MYBPC3 causes early dysfunction in human cell culture models prior to reduced cMyBP-C levels.
摘要
MYBPC3 表达降低会导致人类细胞培养模型在 cMyBP-C 水平降低之前出现早期功能障碍。
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