Suppr超能文献

扁桃体切除术对慢性扁桃体炎患儿炎症及免疫功能的影响

[Effect of tonsillotomy on the inflammation and immune function in children with chronic tonsillitis].

作者信息

Wu Yunwen, Zhang Nannan, Wang Lu, Zhang Qingfeng, Yuan Qing, Wang Xin, Xie Huifen, Lv Jiamu, Li Jinen

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Shenzhen University General Hospital,Shenzhen University Clinical Medical Academy,Shenzhen University,Shenzhen,518055,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Apr;37(4):297-301. doi: 10.13201/j.issn.2096-7993.2023.04.012.

Abstract

To investigate the changes of inflammation and immune function in children with chronic tonsillitis after tonsillotomy. Prospectively collected 60 children with obstructive sleep apnea (OSA) diagnosed as chronic tonsillitis with adenoids and tonsillar hypertrophy from January to June 2021. Two groups were divided, the experimental group (=30) underwent bilateral partial tonsillectomy + adenoidectomy by hypothermia plasma ablation, and the control group (=30) underwent adenoidectomy by using the same hypothermia plasma ablation method. The number of tonsillitis attacks before surgery and within one year after surgery was recorded, and the serum immunoglobulin IgM, IgG, IgA, complement C3 and complement C4 levels before operation, one month and three months after operation were measured. The number of tonsillitis attacks in the experimental group and the control group at one year after surgery was lower than that before surgery(<0.05); The number of inflammatory attacks in the experimental group was (0.50±0.63) times/year, which was lower than that of (1.33±0.80) times/year in the control group. There was no significant difference in the five immunization results of the two groups at one month and three months after operation compared with before operation, and there was also no significant difference between the experimental and the control groups. Partial tonsillectomy can be applied to children with chronic tonsillitis, which can effectively reduce the number of tonsillitis attacks and has no effect on the immune function of children.

摘要

探讨扁桃体切除术后慢性扁桃体炎患儿炎症及免疫功能的变化。前瞻性收集2021年1月至6月诊断为慢性扁桃体炎伴腺样体及扁桃体肥大的60例阻塞性睡眠呼吸暂停(OSA)患儿。分为两组,实验组(n = 30)采用低温等离子消融术行双侧部分扁桃体切除术+腺样体切除术,对照组(n = 30)采用相同的低温等离子消融术行腺样体切除术。记录术前及术后1年内扁桃体炎发作次数,检测术前、术后1个月及3个月血清免疫球蛋白IgM、IgG、IgA、补体C3和补体C4水平。实验组和对照组术后1年扁桃体炎发作次数均低于术前(P<0.05);实验组炎症发作次数为(0.50±0.63)次/年,低于对照组的(1.33±0.80)次/年。两组术后1个月和3个月五项免疫指标结果与术前比较差异无统计学意义,实验组与对照组比较差异也无统计学意义。部分扁桃体切除术可应用于慢性扁桃体炎患儿,能有效减少扁桃体炎发作次数,且对患儿免疫功能无影响。

相似文献

1
[Effect of tonsillotomy on the inflammation and immune function in children with chronic tonsillitis].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Apr;37(4):297-301. doi: 10.13201/j.issn.2096-7993.2023.04.012.
3
[Effect of resection of adenoids and/or tonsil on the immune indexes in children with obstructive sleep apnea hypopnea syndrome].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Nov 7;54(11):830-836. doi: 10.3760/cma.j.issn.1673-0860.2019.11.006.
4
Long term outcome of tonsillar regrowth after partial tonsillectomy in children with obstructive sleep apnea.
Auris Nasus Larynx. 2014 Jun;41(3):299-302. doi: 10.1016/j.anl.2013.12.005. Epub 2014 Jan 1.
5
Comparing postoperative quality of life in children after microdebrider intracapsular tonsillotomy and tonsillectomy.
Auris Nasus Larynx. 2012 Aug;39(4):407-10. doi: 10.1016/j.anl.2011.10.012. Epub 2011 Nov 25.
7
[Immune function alteration in children after tonsillectomy and(or) adenoidectomy].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Mar;30(5):418-23.
8
Tonsillectomy vs. partial tonsillectomy for OSAS in children--10 years post-surgery follow-up.
Int J Pediatr Otorhinolaryngol. 2009 May;73(5):637-40. doi: 10.1016/j.ijporl.2008.12.012. Epub 2009 Jan 22.
9
Coblation® intracapsular tonsillectomy in children with recurrent tonsillitis: Initial experience.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110113. doi: 10.1016/j.ijporl.2020.110113. Epub 2020 May 16.
10
[Tonsillotomy].
Duodecim. 2013;129(15):1555-62.

引用本文的文献

1
[Long-term effect observation after 10 years of tonsillotomy (Histological analysis of one case of secondary operation)].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Sep;38(9):843-848. doi: 10.13201/j.issn.2096-7993.2024.09.013.

本文引用的文献

2
[Clinical practice guidelines for standardized low-temperature plasma radiofrequency ablation tonsillectomy and adenoidectomy in children].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Mar;35(3):193-199. doi: 10.13201/j.issn.2096-7993.2021.03.001.
3
Current Indications for Tonsillectomy and Adenoidectomy.
J Am Board Fam Med. 2020 Nov-Dec;33(6):1025-1030. doi: 10.3122/jabfm.2020.06.200038.
4
Intracapsular coblation tonsillectomy versus extracapsular coblation tonsillectomy: a systematic review and a meta-analysis.
Eur Arch Otorhinolaryngol. 2021 Mar;278(3):637-644. doi: 10.1007/s00405-020-06178-2. Epub 2020 Jul 4.
5
Effect of tonsillectomy on humeral and cellular immunity: a systematic review of published studies from 2009 to 2019.
Eur Arch Otorhinolaryngol. 2020 Jan;277(1):1-7. doi: 10.1007/s00405-019-05672-6. Epub 2019 Oct 29.
6
Tonsillectomy or tonsillotomy? A systematic review for paediatric sleep-disordered breathing.
Int J Pediatr Otorhinolaryngol. 2017 Dec;103:41-50. doi: 10.1016/j.ijporl.2017.10.008. Epub 2017 Oct 5.
7
Coblation versus other surgical techniques for tonsillectomy.
Cochrane Database Syst Rev. 2017 Aug 22;8(8):CD004619. doi: 10.1002/14651858.CD004619.pub3.
8
[Immune function alteration in children after tonsillectomy and(or) adenoidectomy].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Mar;30(5):418-23.
9
The effect of tonsillectomy on the immune system: A systematic review and meta-analysis.
Int J Pediatr Otorhinolaryngol. 2015 Aug;79(8):1184-91. doi: 10.1016/j.ijporl.2015.05.016. Epub 2015 May 27.
10
The influence of tonsillectomy on total serum antibody levels.
Scand J Immunol. 2014 Nov;80(5):377-9. doi: 10.1111/sji.12213.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验