医护专业学生中新冠病毒无症状监测检测：低流行环境中的经验教训。
Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting.
作者信息
Burrows Alyssa G, Linton Sophia, Thiele Jenny, Sheth Prameet M, Evans Gerald A, Archer Stephen, Doliszny Katharine M, Finlayson Marcia, Flynn Leslie, Huang Yun, Kasmani Azim, Hugh Guan T, Maier Allison, Hansen-Taugher Adrienne, Moore Kieran, Sanfilippo Anthony, Snelgrove-Clarke Erna, Tripp Dean A, Walker David M C, Vanner Stephen, Ellis Anne K
机构信息
Department of Medicine, Queen's University, Kingston, ON, Canada.
Allergy Research Unit, Watkins 1D, Kingston Health Sciences Centre-KGH Site, 76 Stuart, Kingston, ON, K7L2V7, Canada.
出版信息
Allergy Asthma Clin Immunol. 2023 Mar 29;19(1):25. doi: 10.1186/s13223-023-00769-4.
The novel coronavirus disease of 2019 (COVID-19) pandemic has severely impacted the training of health care professional students because of concerns of potential asymptomatic transmission to colleagues and vulnerable patients. From May 27th, 2020, to June 23rd 2021; at a time when B.1.1.7 (alpha) and B.1.617.2 (delta) were the dominant circulating variants, PCR testing was conducted on 1,237 nasopharyngeal swabs collected from 454 asymptomatic health care professional students as they returned to their studies from across Canada to Kingston, ON, a low prevalence area during that period for COVID-19. Despite 46.7% of COVID-19 infections occurring in the 18-29 age group in Kingston, severe-acute-respiratory coronavirus-2 was not detected in any of the samples suggesting that negligible asymptomatic infection occurred in this group and that PCR testing in this setting may not be warranted as a screening tool.
2019年新型冠状病毒病（COVID-19）大流行严重影响了医护专业学生的培训，因为担心可能会将无症状感染传播给同事和易感染患者。在2020年5月27日至2021年6月23日期间；当时B.1.1.7（阿尔法）和B.1.617.2（德尔塔）是主要的流行变体，对从加拿大各地返回安大略省金斯敦复学的454名无症状医护专业学生采集的1237份鼻咽拭子进行了PCR检测，金斯敦在那段时间是COVID-19的低流行地区。尽管金斯敦18至29岁年龄组的COVID-19感染率为46.7%，但在任何样本中均未检测到严重急性呼吸综合征冠状病毒2，这表明该组中无症状感染可忽略不计，在这种情况下，PCR检测作为一种筛查工具可能没有必要。
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