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妊娠发热性坏死性蕈样肉芽肿病:一例报告。

Febrile ulceronecrotic Mucha-Habermann disease during pregnancy: A case report.

机构信息

Department of Dermatology and Venereology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey.

Department of Pathology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey.

出版信息

Australas J Dermatol. 2023 May;64(2):245-248. doi: 10.1111/ajd.14028. Epub 2023 Apr 1.

Abstract

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare and severe form of 'pityriasis lichenoides et varioliformis acuta', with a progressive and potentially fatal course. To the best of our knowledge, there has been no reported case of FUMDH during pregnancy before. Due to life-threatening nature of the disease and the lack of evidence-based treatment, management of FUMHD in pregnancy is a therapeutic challenge. Additionally, some of the drugs that are effective in the treatment are contraindicated in pregnancy. Herein, we report a 27-year-old woman diagnosed with FUMHD in her 19th week of pregnancy and treated with ceftriaxone and erythromycin.

摘要

发热性溃疡性坏死性蕈样肉芽肿病(FUMHD)是一种罕见且严重的“急性痘疮样苔藓样糠疹”形式,具有进行性和潜在致命的病程。据我们所知,以前从未有过妊娠期 FUMHD 的报道。由于疾病的致命性质和缺乏循证治疗,妊娠期间 FUMHD 的治疗是一个治疗挑战。此外,一些在治疗中有效的药物在妊娠期间是禁忌的。在此,我们报告了一例 27 岁的女性,她在妊娠 19 周时被诊断为 FUMHD,并接受了头孢曲松和红霉素治疗。

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