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口服营养补充对髋部骨折术后患者临床结局的影响:文献综述。

Effects of the use of oral nutrition supplements on clinical outcomes among patients who have undergone surgery for hip fracture: A literature review.

机构信息

Department of Clinical and Preventive Nutrition Sciences, Rutgers University School of Health Professions, Newark, New Jersey, USA.

出版信息

Nutr Clin Pract. 2023 Aug;38(4):775-789. doi: 10.1002/ncp.10980. Epub 2023 Apr 4.

Abstract

Older adults who have undergone surgery for hip fracture are often malnourished or at risk for malnutrition, and providing oral nutrition supplements is a common intervention used to help meet nutrition needs postoperatively among this population. A literature search was conducted to examine the effects of oral nutrition supplementation on postoperative outcomes among patients ≥55 years old who had undergone surgery for hip fracture. Three randomized controlled trials that met inclusion criteria are examined in this review. Findings suggest that the use of oral nutrition supplements is not associated with decreased hospital length of stay but is associated with improvements in markers of sarcopenia and functional status. Additionally, the literature implies that oral nutrition supplements containing calcium beta-hydroxy-beta-methylbutyrate may have the most benefit for improving postoperative outcomes. This review concludes that oral nutrition supplement use can be incorporated as a part of routine protocols for patients who have had surgery to repair a hip fracture. However, given some inconsistent findings, future research is needed to support the inclusion of oral nutrtition supplement use in clinical practice guidelines for this population. Furthermore, future research should explore how the use of oral nutrition supplements with calcium beta-hydroxy-beta-methylbutyrate compares with the use of oral nutrition supplements without this ingredient.

摘要

接受髋关节骨折手术的老年人常常存在营养不良或有发生营养不良的风险,而提供口服营养补充剂是一种常见的干预措施,用于帮助满足该人群术后的营养需求。本文进行了文献检索,以评估口服营养补充对≥55 岁接受髋关节骨折手术的患者术后结局的影响。本综述检查了符合纳入标准的三项随机对照试验。结果表明,口服营养补充剂的使用与住院时间缩短无关,但与肌少症和功能状态标志物的改善有关。此外,文献表明,含有钙 β-羟基-β-甲基丁酸的口服营养补充剂可能对改善术后结局最有益。本综述得出结论,对于接受髋关节骨折修复手术的患者,可以将口服营养补充剂的使用纳入常规方案。然而,鉴于一些结果不一致,需要进一步的研究来支持将口服营养补充剂的使用纳入该人群的临床实践指南。此外,未来的研究应探讨使用含有钙 β-羟基-β-甲基丁酸的口服营养补充剂与不使用该成分的口服营养补充剂相比的效果。

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