Worhacz Kellen M, Carter Thomas R
University of Arizona- Phoenix, 623-210-2560, 1320 N 10thSt, Ste A, Phoenix, AZ, 85006, USA.
Clinical Professor of Orthopedic Surgery, University of AZ - Phoenix, 602 521-3250, 755 E McDowell Rd, Phoenix, Arizona, 85006, USA.
Curr Rev Musculoskelet Med. 2023 May;16(5):163-172. doi: 10.1007/s12178-023-09825-3. Epub 2023 Apr 4.
Meniscal allograft transplantation is intended to address painful knees with symptoms that can be attributed to meniscal deficiency through injury or meniscectomy. Initially viewed as an experimental procedure, refinements in patient selection and surgical technique have led to improved clinical outcomes with wider acceptance. Our intention with this paper is to provide a review of meniscal allograft transplantation, with the focus on the different surgical techniques employed and their influence on outcomes.
The main debate regarding surgical technique is using bone or only soft tissue for fixation of the meniscal horns. Biomechanical and other basic science studies show improved function and less extrusion when the grafts are secured with bone. However, several clinical studies show no difference in outcomes. Long-term studies have shown improved success with less graft extrusion and may illustrate the important function of bone fixation. Many clinical studies, including those with long-term outcomes, have shown meniscal allografts can decrease patient pain and improve function. It is a technically challenging procedure with good clinical outcomes regardless of the method of graft fixation. Bone fixation provides less extrusion which is associated with improved graft function and decreased rate of joint deterioration. Further study is needed to determine if other methods to decrease extrusion are able to improve graft function and outcomes.
半月板同种异体移植旨在治疗因损伤或半月板切除术导致半月板缺失而出现疼痛症状的膝关节。最初被视为一种实验性手术,随着患者选择和手术技术的改进,临床疗效得到改善,其接受度也越来越高。本文旨在对半月板同种异体移植进行综述,重点关注所采用的不同手术技术及其对疗效的影响。
关于手术技术的主要争论在于半月板角固定时是使用骨组织还是仅使用软组织。生物力学和其他基础科学研究表明,使用骨组织固定移植物时功能改善且挤压减少。然而,多项临床研究表明疗效并无差异。长期研究显示成功率提高,移植物挤压减少,这可能说明了骨固定的重要作用。许多临床研究,包括那些有长期疗效的研究,均表明半月板同种异体移植可减轻患者疼痛并改善功能。无论移植物固定方法如何,这都是一项技术要求高但临床疗效良好的手术。骨固定可减少挤压,这与移植物功能改善和关节退变率降低相关。需要进一步研究以确定其他减少挤压的方法是否能够改善移植物功能和疗效。