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靶向注射富含血小板血浆(PRP)联合皮肤增强剂治疗面部衰老的临床疗效及安全性。

Clinical efficacy and safety of targeted injection of PRP with skin booster in the treatment of aging face.

机构信息

Dermatology Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

出版信息

Biotechnol Genet Eng Rev. 2024 Nov;40(3):2196-2212. doi: 10.1080/02648725.2023.2199233. Epub 2023 Apr 10.

Abstract

Platelet-rich plasma (PRP) with skin booster is a popular treatment for improving skin quality and reducing the signs of aging. However, few studies have evaluated its clinical efficacy in patients with aging face. This study aimed to evaluate the clinical efficacy, adverse reactions, and follow-up results of targeted injection of PRP with skin booster in treating patients with aging face. The study included 80 patients treated with targeted injection of PRP with skin booster from July 2022 to February 2023. The doctors compared the changes of the patients' facial skin indicators, quality of life, and satisfaction with their appearance before and after treatment, and analyzed the clinical efficacy, adverse reactions, and follow-up results of the patients after treatment. After one course of treatment, the patients' facial skin indicators, quality of life, and satisfaction with their appearance improved significantly, with  < 0.05. The total clinical effective rate was 88.75%, and the incidence of adverse reactions was 6.25%. After half a year of follow-up, 48.75% of the patients were willing to receive further treatment, and their facial soft feel, natural expression, and self-feeling comfort had significantly improved. Targeted injection of PRP with skin booster is an effective and safe treatment for improving facial skin symptoms such as coarse pores and wrinkles in patients with aging face. The results of this study provide evidence for the clinical use of PRP with skin booster in aesthetic medicine.

摘要

富血小板血浆(PRP)与皮肤增强剂是一种流行的治疗方法,可改善皮肤质量并减少衰老迹象。然而,很少有研究评估其在衰老面部患者中的临床疗效。本研究旨在评估靶向注射 PRP 与皮肤增强剂治疗衰老面部患者的临床疗效、不良反应和随访结果。该研究纳入了 2022 年 7 月至 2023 年 2 月接受靶向注射 PRP 与皮肤增强剂治疗的 80 例患者。医生比较了患者面部皮肤指标、生活质量和对外观的满意度在治疗前后的变化,并分析了患者治疗后的临床疗效、不良反应和随访结果。经过一个疗程的治疗,患者的面部皮肤指标、生活质量和对外观的满意度均显著改善, < 0.05。总临床有效率为 88.75%,不良反应发生率为 6.25%。半年随访时,48.75%的患者愿意接受进一步治疗,其面部柔软感、自然表情和自我感觉舒适度均显著改善。靶向注射 PRP 与皮肤增强剂是改善衰老面部患者毛孔粗大和皱纹等面部皮肤症状的有效且安全的治疗方法。本研究结果为 PRP 与皮肤增强剂在美容医学中的临床应用提供了证据。

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