From the Division of Plastic and Reconstructive Surgery, The Warren Alpert Medical School of Brown University.
Plast Reconstr Surg. 2024 Jan 1;153(1):130e-138e. doi: 10.1097/PRS.0000000000010524. Epub 2023 Apr 11.
In cleft palate repair, palate length is associated with improved speech outcomes. Although direct closure offers poor palatal lengthening, use of two opposing Z-plasties may reorient palatal musculature and lengthen the velum. The authors previously described a novel overlapping intravelar veloplasty to achieve longitudinal closure of the nasal mucosa with a single oral Z-plasty (1ZP), lengthening the palate in cadaver studies. This study aims to corroborate this finding in clinical cases.
A retrospective comparative study of patients with a cleft palate was conducted. Patients underwent cleft palate closure with 1ZP or intravelar veloplasty with straight-line closure. Preoperative and postoperative measurements of the palate along four dimensions were recorded. Analysis was conducted on preoperative and postoperative measurements within and between groups using the Mann-Whitney-Wilcoxon or chi-square test.
Eighty-five patients were included (1ZP, n = 65; straight-line closure, n = 20). 1ZP increased soft palate length (SPL) by 33% ( P < 0.001) and total palate length (TPL) by 10% ( P < 0.001). Primary 1ZP increased SPL by 33% ( P < 0.001) and TPL by 10% ( P < 0.001). Secondary 1ZP increased SPL by 28% ( P < 0.001) and TPL by 8% ( P < 0.001). When comparing between primary and secondary 1ZP, 1ZP was equal with regard to percentage lengthening in SPL ( P > 0.9) and TPL ( P > 0.3). When compared with straight-line closure, 1ZP showed superior percentage lengthening in SPL ( P < 0.001) and TPL ( P = 0.038).
1ZP results in a statistically significant increase in palate length in both primary and secondary cleft palate repair. This technique provides an effective alternative in patients for whom 2ZP is not feasible.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
在腭裂修复中,腭裂长度与改善语音结果有关。虽然直接闭合提供的腭长度改善效果不佳,但是使用两个相对的 Z 成形术可能会重新定向腭部肌肉并延长软腭。作者之前描述了一种新的重叠腔内软腭裂成形术,通过单个口腔 Z 成形术(1ZP)实现鼻腔黏膜的纵向闭合,从而在尸体研究中延长腭部。本研究旨在通过临床病例来证实这一发现。
对腭裂患者进行了回顾性比较研究。患者接受 1ZP 或直线闭合的腔内软腭裂成形术进行腭裂修复。记录术前和术后四个维度的腭部测量值。使用 Mann-Whitney-Wilcoxon 或卡方检验对内组和组间的术前和术后测量值进行分析。
共纳入 85 例患者(1ZP 组,n=65;直线闭合组,n=20)。1ZP 使软腭长度(SPL)增加 33%(P<0.001),总腭长度(TPL)增加 10%(P<0.001)。初次 1ZP 使 SPL 增加 33%(P<0.001),TPL 增加 10%(P<0.001)。二次 1ZP 使 SPL 增加 28%(P<0.001),TPL 增加 8%(P<0.001)。当比较初次和二次 1ZP 时,1ZP 在 SPL(P>0.9)和 TPL(P>0.3)的百分比伸长方面是相等的。与直线闭合相比,1ZP 在 SPL(P<0.001)和 TPL(P=0.038)的百分比伸长方面具有更好的效果。
1ZP 可使初次和二次腭裂修复后的腭长度均有统计学显著增加。对于不适合行 2ZP 的患者,该技术是一种有效的替代方法。
临床问题/证据水平:治疗性,III 级。