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单瓣口 Z 成形术:腭裂修复中一种用于腭部延长的技术的临床验证。

Single Oral Z-Plasty: A Clinical Validation of a Technique for Palatal Lengthening in Primary and Secondary Cleft Palate Repair.

机构信息

From the Division of Plastic and Reconstructive Surgery, The Warren Alpert Medical School of Brown University.

出版信息

Plast Reconstr Surg. 2024 Jan 1;153(1):130e-138e. doi: 10.1097/PRS.0000000000010524. Epub 2023 Apr 11.

Abstract

BACKGROUND

In cleft palate repair, palate length is associated with improved speech outcomes. Although direct closure offers poor palatal lengthening, use of two opposing Z-plasties may reorient palatal musculature and lengthen the velum. The authors previously described a novel overlapping intravelar veloplasty to achieve longitudinal closure of the nasal mucosa with a single oral Z-plasty (1ZP), lengthening the palate in cadaver studies. This study aims to corroborate this finding in clinical cases.

METHODS

A retrospective comparative study of patients with a cleft palate was conducted. Patients underwent cleft palate closure with 1ZP or intravelar veloplasty with straight-line closure. Preoperative and postoperative measurements of the palate along four dimensions were recorded. Analysis was conducted on preoperative and postoperative measurements within and between groups using the Mann-Whitney-Wilcoxon or chi-square test.

RESULTS

Eighty-five patients were included (1ZP, n = 65; straight-line closure, n = 20). 1ZP increased soft palate length (SPL) by 33% ( P < 0.001) and total palate length (TPL) by 10% ( P < 0.001). Primary 1ZP increased SPL by 33% ( P < 0.001) and TPL by 10% ( P < 0.001). Secondary 1ZP increased SPL by 28% ( P < 0.001) and TPL by 8% ( P < 0.001). When comparing between primary and secondary 1ZP, 1ZP was equal with regard to percentage lengthening in SPL ( P > 0.9) and TPL ( P > 0.3). When compared with straight-line closure, 1ZP showed superior percentage lengthening in SPL ( P < 0.001) and TPL ( P = 0.038).

CONCLUSIONS

1ZP results in a statistically significant increase in palate length in both primary and secondary cleft palate repair. This technique provides an effective alternative in patients for whom 2ZP is not feasible.

CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

摘要

背景

在腭裂修复中,腭裂长度与改善语音结果有关。虽然直接闭合提供的腭长度改善效果不佳,但是使用两个相对的 Z 成形术可能会重新定向腭部肌肉并延长软腭。作者之前描述了一种新的重叠腔内软腭裂成形术,通过单个口腔 Z 成形术(1ZP)实现鼻腔黏膜的纵向闭合,从而在尸体研究中延长腭部。本研究旨在通过临床病例来证实这一发现。

方法

对腭裂患者进行了回顾性比较研究。患者接受 1ZP 或直线闭合的腔内软腭裂成形术进行腭裂修复。记录术前和术后四个维度的腭部测量值。使用 Mann-Whitney-Wilcoxon 或卡方检验对内组和组间的术前和术后测量值进行分析。

结果

共纳入 85 例患者(1ZP 组,n=65;直线闭合组,n=20)。1ZP 使软腭长度(SPL)增加 33%(P<0.001),总腭长度(TPL)增加 10%(P<0.001)。初次 1ZP 使 SPL 增加 33%(P<0.001),TPL 增加 10%(P<0.001)。二次 1ZP 使 SPL 增加 28%(P<0.001),TPL 增加 8%(P<0.001)。当比较初次和二次 1ZP 时,1ZP 在 SPL(P>0.9)和 TPL(P>0.3)的百分比伸长方面是相等的。与直线闭合相比,1ZP 在 SPL(P<0.001)和 TPL(P=0.038)的百分比伸长方面具有更好的效果。

结论

1ZP 可使初次和二次腭裂修复后的腭长度均有统计学显著增加。对于不适合行 2ZP 的患者,该技术是一种有效的替代方法。

临床问题/证据水平:治疗性,III 级。

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