Dementia Centre for Research Collaboration, Sydney, Australia.
Neuroscience Research Australia, Margarete Ainsworth Building, 139 Barker Street, Randwick, Sydney, NSW, 2031, Australia.
Alzheimers Res Ther. 2023 Apr 10;15(1):76. doi: 10.1186/s13195-023-01219-4.
Advances in pharmacological and non-pharmacological dementia interventions may mean future dementia prevention incorporates a combination of targeted screening and lifestyle modifications. Elucidating potential barriers which may prevent community engagement with dementia prevention initiatives is important to maximise the accessibility and feasibility of these initiatives across the lifespan.
Six hundred seven adults aged over 18 years completed a 54-item, multiple-choice survey exploring contemporary attitudes towards, and barriers to, dementia risk reduction and screening relative to other common health conditions. Participants were sourced from Australia's largest, paid, data analytics service (ORIMA).
Finances (p = .009), poor motivation (p = .043), and time (p ≤ .0001) emerged as significant perceived barriers to dementia risk reduction behaviours. Lack of time was more likely to be reported by younger, relative to older, participants (p ≤ .0001), while females were more likely than males to report financial (p = .019) and motivational (p = .043) factors. Binary logistic regression revealed willingness to undertake dementia testing modalities was significantly influenced by gender (genetic testing, p = .012; saliva, p = .038, modifiable risk factors p = .003), age (cognitive testing, p ≤ .0001; blood, p = .010), and socio-economic group (retinal imaging, p = .042; modifiable risk-factor screening, p = .019). Over 65% of respondents felt adequately informed about risk reduction for at least one non-dementia health condition, compared to 30.5% for dementia.
This study found perceived barriers to dementia risk reduction behaviours, and the willingness to engage in various dementia testing modalities, was significantly associated with socio-demographic factors across the lifespan. These findings provide valuable insight regarding the accessibility and feasibility of potential methods for identifying those most at risk of developing dementia, as well as the need to better promote and support wide-scale engagement in dementia risk reduction behaviours across the lifespan.
在药理学和非药理学痴呆干预方面的进步可能意味着未来的痴呆预防将结合有针对性的筛查和生活方式改变。阐明可能阻碍社区参与痴呆预防计划的潜在障碍对于最大限度地提高这些计划在整个生命周期内的可及性和可行性非常重要。
607 名年龄在 18 岁以上的成年人完成了一项 54 项多项选择题调查，该调查探讨了相对于其他常见健康状况，他们对降低痴呆风险和筛查的态度以及对降低痴呆风险和筛查的障碍。参与者来自澳大利亚最大的付费数据分析服务（ORIMA）。
财务状况（p=.009）、缺乏动机（p=.043）和时间（p≤.0001）是降低痴呆风险行为的显著感知障碍。与年龄较大的参与者相比，年轻参与者更有可能报告时间不足（p≤.0001），而女性比男性更有可能报告财务（p=.019）和动机（p=.043）因素。二元逻辑回归显示，愿意进行痴呆检测模式显著受到性别（遗传检测，p=.012；唾液，p=.038，可改变的风险因素，p=.003）、年龄（认知测试，p≤.0001；血液，p=.010）和社会经济群体（视网膜成像，p=.042；可改变的风险因素筛查，p=.019）的影响。超过 65%的受访者认为自己对至少一种非痴呆健康状况的风险降低有足够的了解，而对痴呆的了解则为 30.5%。
本研究发现，降低痴呆风险行为的感知障碍以及参与各种痴呆检测模式的意愿与整个生命周期的社会人口因素显著相关。这些发现为识别最有可能患上痴呆症的人的潜在方法的可及性和可行性提供了有价值的见解，以及在整个生命周期内更好地促进和支持广泛参与痴呆风险降低行为的必要性。
