Department of Rehabilitation, Hitachi General Hospital, Japan.
Department of Psychiatry, Yamagata University School of Medicine, Japan.
Intern Med. 2023 Nov 15;62(22):3405-3412. doi: 10.2169/internalmedicine.0023-22. Epub 2023 Apr 14.
Cerebellar injuries can cause syntax impairments. Cortical dysfunction due to cerebello-cerebral diaschisis is assumed to play a role in this phenomenon. Functional magnetic resonance imaging studies have repeatedly shown the activation of Broca's area in response to syntactic tasks. However, there have been no reports of selective syntax impairment and hypoperfusion restricted to this area after cerebellar injury. We herein report a patient with right cerebellar hemorrhage that led to marked syntax impairment along with severe hypoperfusion confined to the Brodmann area (BA) 45 (anterior part of Broca's area) and BA46.
小脑损伤可导致句法障碍。由于小脑-大脑失联络,皮质功能障碍被认为在这种现象中起作用。功能磁共振成像研究反复表明,在句法任务中布罗卡区(Broca's area)的激活。然而,在小脑损伤后,尚未有选择性句法障碍和仅局限于该区域的灌注不足的报道。我们在此报告一例右侧小脑出血患者,其表现为明显的句法障碍,同时伴有局限于布罗德曼区(BA)45(布罗卡区的前部)和 BA46 的严重灌注不足。