Department of Surgery, National Cheng Kung University Hospital, College of Medicine, Institute of Clinical Medicine, National Cheng Kung University, 138, Sheng-Li Road, Tainan, 70428, Taiwan.
Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, 35 Siaodong Road, Tainan, 70457, Taiwan.
Sci Rep. 2023 Apr 16;13(1):6190. doi: 10.1038/s41598-023-33269-x.
Laparoscopic (LPD) and robotic pancreaticoduodenectomy (RPD) are both challenging procedures. The feasibility and safety of simultaneously developing LPD and RPD remain unreported. We retrospectively reviewed the data of patients undergoing LPD or RPD between 2014 and 2021. A total of 114 patients underwent minimally invasive pancreaticoduodenectomy (MIPD): 39 LPDs and 75 RPDs. The learning process of LPD and RPD were similar. The cutoff points of the learning curve were LPD, 13th patient (the 27th patient of MIPD), and RPD, 18th patient (the 31st patient of MIPD) according the cumulative sum analysis of operative time. A decrease in the operative time was associated with the case sequence (p < 0.001) but not with the surgical approach (p = 0.36). The overall surgical outcomes were comparable between both the LPD and RPD groups. When evaluating the learning curve impact on MIPD, LPD had higher major complication (≧ Clavien-Dindo grade III), bile leak and wound infection rates in the pre-learning curve phase than those in the after-learning curve phase, while RPD had similar surgical outcomes between two phases. Simultaneous development of LPD and RPD is feasible and safe for experienced surgeons, with similar learning process and comparable surgical outcomes.
腹腔镜(LPD)和机器人胰十二指肠切除术(RPD)都是具有挑战性的手术。同时开展 LPD 和 RPD 的可行性和安全性尚未报道。我们回顾性分析了 2014 年至 2021 年间接受 LPD 或 RPD 的患者数据。共有 114 例患者接受了微创胰十二指肠切除术(MIPD):39 例 LPD 和 75 例 RPD。LPD 和 RPD 的学习过程相似。根据手术时间累积和分析,LPD 的学习曲线切点为第 13 例患者(MIPD 的第 27 例患者),RPD 的学习曲线切点为第 18 例患者(MIPD 的第 31 例患者)。手术时间的减少与病例序列有关(p<0.001),但与手术方式无关(p=0.36)。两组的总体手术结果相当。当评估学习曲线对 MIPD 的影响时,在学习曲线前阶段,LPD 的主要并发症(≧Clavien-Dindo 分级 III)、胆漏和伤口感染率高于学习曲线后阶段,而 RPD 在两个阶段的手术结果相似。对于经验丰富的外科医生来说,同时开展 LPD 和 RPD 是可行且安全的,具有相似的学习过程和相当的手术结果。