Zheng Yuhang, Li Yang, Tian Hua
Department of Orthopedics, Peking University Third Hospital, Beijing, 100191, P. R. China.
Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, 100191, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Apr 15;37(4):502-506. doi: 10.7507/1002-1892.202211105.
To review the research progress of injection sites of local infiltration analgesia (LIA) in total knee arthroplasty (TKA).
The relevant domestic and foreign literature in recent years was extensively reviewed. The neuroanatomy of the knee, and the research progress of the selection and the difference of effectiveness between different injection sites of LIA in clinical studies were summarized.
Large concentrations of nociceptors are present throughout the various tissues of the knee joint. Patellar tendon, subpatellar fat pad, lateral collateral ligament insertions, iliotibial band insertions, suprapatellar capsule, and posterior capsule were more sensitive to pain. Most current studies support injections into the lateral capsule, collateral ligament, retinaculum, quadriceps tendon, fat pad, and subcutaneous tissue. Whether to inject into the back of the knee and subperiosteum is controversial.
The relative difference of knee tissue sensitivity to pain has guiding significance for the selection of LIA injection site after TKA. Although researchers have conducted clinical trials on injection site and technique of LIA in TKA, there are certain limitations. The optimal scheme has not been determined yet, and further studies are needed.
回顾全膝关节置换术(TKA)中局部浸润镇痛(LIA)注射部位的研究进展。
广泛查阅近年来国内外相关文献。总结膝关节的神经解剖结构,以及临床研究中LIA不同注射部位的选择及效果差异的研究进展。
膝关节的各种组织中均存在大量伤害感受器。髌腱、髌下脂肪垫、外侧副韧带附着点、髂胫束附着点、髌上囊和后囊对疼痛更敏感。目前大多数研究支持注射到外侧关节囊、副韧带、支持带、股四头肌肌腱、脂肪垫和皮下组织。是否注射到膝关节后方和骨膜下存在争议。
膝关节组织对疼痛的相对差异对TKA术后LIA注射部位的选择具有指导意义。尽管研究人员已对TKA中LIA的注射部位和技术进行了临床试验,但存在一定局限性。尚未确定最佳方案,需要进一步研究。