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中医身心锻炼对认知障碍老年人的影响:系统评价与荟萃分析

Effects of traditional Chinese mind-body exercises on older adults with cognitive impairment: A systematic review and meta-analysis.

作者信息

Yao Ke-Ru, Luo Qin, Tang Xi, Wang Zhi-Han, Li Lu, Zhao Lu, Zhou Li, Li Ling, Huang Li, Yin Xin-Hong

机构信息

School of Nursing, University of South China, Hengyan, China.

Second Affiliated Hospital of University of South China, Hengyang, Hunan, China.

出版信息

Front Neurol. 2023 Apr 3;14:1086417. doi: 10.3389/fneur.2023.1086417. eCollection 2023.

Abstract

OBJECTIVE

To determine the effectiveness of traditional Chinese mind-body exercises in improving cognition, memory, and executive function in older adults with cognitive impairment.

DATA SOURCES

Relevant English and Chinese language studies published until September 14th, 2022 were retrieved from PubMed, Web of Science, Cochrane Library, Embase, CINAHL, WAN FANG DATA, VIP Information, CNKI, and SinoMed databases.

REVIEW METHODS

Randomized controlled trials assessing traditional Chinese mind-body exercises (Tai Chi, Baduanjin, Qigong, Mind-Body Therapies, and Yijinjing) in older adults with cognitive impairment were included. Two researchers independently identified eligible studies and extracted data. A risk-of-bias assessment was performed using the Cochrane Risk of Bias Tool.

RESULTS

This study included 15 randomized controlled trials (1,127 participants) from China, Thailand and American. Most studies had a high risk of bias in the blinding of participants and researchers, one study had a high risk of bias in the random sequence generation and two studies had a high risk of bias in the incomplete outcome data. Compared with conventional therapy alone, traditional Chinese mind-body exercises significantly improved global cognitive function ( < 0.00001), and Baduanjin could improve the global cognitive function ( < 0.00001), memory function ( < 0.0001), and executive function ( < 0.0001) outcomes after treatment, and significantly improved some dimensional scores on the auditory verbal learning test after treatment ( = 0.04).

CONCLUSION

Compared with conventional therapy, traditional Chinese mind-body exercises (Tai Chi, Baduanjin, and Qigong) significantly improved global cognitive function, and Baduanjin could improve global cognitive function, memory function, and executive function in older adults with cognitive impairment.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/PROSPERO/#searchadvanced, CRD42022327563.

摘要

目的

确定中医身心锻炼对改善认知功能受损老年人的认知、记忆和执行功能的有效性。

数据来源

从PubMed、科学网、考科蓝图书馆、Embase、护理学与健康领域数据库、万方数据、维普资讯、中国知网和中国生物医学文献数据库中检索截至2022年9月14日发表的相关英文和中文研究。

综述方法

纳入评估中医身心锻炼(太极拳、八段锦、气功、身心疗法和易筋经)对认知功能受损老年人影响的随机对照试验。两名研究人员独立识别符合条件的研究并提取数据。使用考科蓝偏倚风险工具进行偏倚风险评估。

结果

本研究纳入了来自中国、泰国和美国的15项随机对照试验(1127名参与者)。大多数研究在参与者和研究人员的盲法方面存在高偏倚风险,一项研究在随机序列生成方面存在高偏倚风险,两项研究在不完整结果数据方面存在高偏倚风险。与单纯常规治疗相比,中医身心锻炼显著改善了整体认知功能(<0.00001),八段锦可改善治疗后的整体认知功能(<0.00001)、记忆功能(<0.0001)和执行功能(<0.0001)结果,并显著改善治疗后听觉词语学习测试的一些维度得分(=0.04)。

结论

与常规治疗相比,中医身心锻炼(太极拳、八段锦和气功)显著改善了整体认知功能,八段锦可改善认知功能受损老年人的整体认知功能、记忆功能和执行功能。

系统综述注册

https://www.crd.york.ac.uk/PROSPERO/#searchadvanced,CRD42022327563。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2080/10106716/3c36e04d01b2/fneur-14-1086417-g001.jpg

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