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在纽约市接受 Ryan White 服务的 HIV 感染者中的年轻成年人的持久病毒抑制。

Durable Viral Suppression Among Young Adults Living with HIV Receiving Ryan White Services in New York City.

机构信息

New York City Department of Health and Mental Hygiene, Bureau of Hepatitis, HIV, and Sexually Transmitted Infections, Queens, NY, USA.

JEVS Human Services, 1845 Walnut Street, Philadelphia, PA, 19103, USA.

出版信息

AIDS Behav. 2023 Oct;27(10):3197-3205. doi: 10.1007/s10461-023-04040-0. Epub 2023 Apr 21.


DOI:10.1007/s10461-023-04040-0
PMID:37084103
Abstract

Identifying factors associated with durable viral suppression (DVS) can inform interventions to support young adults living with HIV (YALWH) in sustaining optimal health. We examined associations between client characteristics and DVS among YALWH aged 18-29 who completed an intake assessment and received ≥ 1 Ryan White Part A service in New York City from 1/2017 to 12/2019. Individuals were classified as achieving DVS at least once if they had ≥ 2 suppressed viral load test results ≥ 90 days apart with: (a) no intervening unsuppressed viral load test results in a 12-month period; and (b) no unsuppressed viral load test results after achieving DVS in that 12-month period. Of 2208 YALWH, 92.1% (n = 2034) had sufficient data in the New York City HIV Surveillance Registry to ascertain DVS status. Of these, 68% achieved DVS at least once. Controlling for ART prescription status at intake, YALWH with higher incomes were significantly more likely to achieve DVS at least once. YALWH with lifetime and recent histories of incarceration and/or drug use were significantly less likely to achieve DVS. Our findings underscore the potential role of tailored harm reduction and post-incarceration programs in reducing health inequities among YALWH.

摘要

确定与持久病毒抑制(DVS)相关的因素可以为支持感染艾滋病毒的年轻成年人(YALWH)维持最佳健康的干预措施提供信息。我们研究了在 2017 年 1 月至 2019 年 12 月期间在纽约市完成了摄入评估并接受了至少一次 Ryan White 第一部分服务的 18-29 岁 YALWH 中,客户特征与 DVS 之间的关联。如果个体至少有两次相隔至少 90 天的抑制病毒载量测试结果满足以下条件,则将其归类为至少一次达到 DVS:(a) 在 12 个月内没有中间未抑制的病毒载量测试结果;以及 (b) 在达到 DVS 的 12 个月内没有未抑制的病毒载量测试结果。在 2208 名 YALWH 中,92.1%(n=2034)在纽约市艾滋病毒监测登记处有足够的数据来确定 DVS 状态。其中,68%的人至少达到了一次 DVS。在控制摄入时 ART 处方状况后,收入较高的 YALWH 更有可能至少达到一次 DVS。有终身和近期监禁和/或吸毒史的 YALWH 不太可能达到 DVS。我们的研究结果强调了量身定制的减少伤害和监禁后计划在减少 YALWH 中的健康不平等方面的潜在作用。

相似文献

[1]
Durable Viral Suppression Among Young Adults Living with HIV Receiving Ryan White Services in New York City.

AIDS Behav. 2023-10

[2]
Service utilization and HIV outcomes among transgender women receiving Ryan White Part A services in New York City.

PLoS One. 2021

[3]
Impact of an HIV Care Coordination Program on Durable Viral Suppression.

J Acquir Immune Defic Syndr. 2019-1-1

[4]
Continuum of Care Among People Living with Perinatally Acquired HIV Infection in New York City, 2014.

Public Health Rep. 2016

[5]
Characterizing Ryan White Part A-funded support service utilization patterns and their association with viral suppression among people with HIV in New York City.

AIDS Behav. 2022-10

[6]
Associations between drug use patterns and viral load suppression among HIV-positive individuals who use support services in New York City.

Drug Alcohol Depend. 2019-1-15

[7]
Place-based predictors of HIV viral suppression and durable suppression among heterosexuals in New York city.

AIDS Care. 2019-7

[8]
Correlates of Durable Viral Suppression (DVS) Among Criminal Justice-involved (CJI) Black Men Living with HIV in Louisiana.

AIDS Behav. 2019-11

[9]
Durable Viral Suppression Among People with HIV and Problem Substance Use in the Era of Universal Antiretroviral Treatment.

AIDS Behav. 2022-2

[10]
Multilevel Factors Associated with a Lack of Viral Suppression Among Persons Living with HIV in a Federally Funded Housing Program.

AIDS Behav. 2019-3

本文引用的文献

[1]
Brief Report: Racial and Ethnic Disparities in Sustained Viral Suppression and Transmission Risk Potential Among Persons Aged 13-29 Years Living With Diagnosed HIV Infection, United States, 2016.

J Acquir Immune Defic Syndr. 2020-4-1

[2]
Individual and neighborhood predictors of retention in care and viral suppression among Florida youth (aged 13-24) living with HIV in 2015.

Int J STD AIDS. 2019-10

[3]
Predictors of viral suppression among youth living with HIV in the southern United States.

AIDS Care. 2020-7

[4]
Housing Instability, Depression, and HIV Viral Load Among Young Black Gay, Bisexual, and Other Men Who Have Sex With Men in Atlanta, Georgia.

J Assoc Nurses AIDS Care. 2020

[5]
Nonadherence and unsuppressed viral load across adolescence among US youth with perinatally acquired HIV.

AIDS. 2019-10-1

[6]
Health Knowledge and Adherence as Predictors of Viral Burden and CD4+ T-Cell Count in Youth and Young Adults Living With HIV.

J Assoc Nurses AIDS Care. 2020

[7]
Food Insecurity and Unmet Needs Among Youth and Young Adults Living With HIV in the San Francisco Bay Area.

J Adolesc Health. 2019-6-10

[8]
Characteristics and Care Outcomes Among Persons Living With Perinatally Acquired HIV Infection in the United States, 2015.

J Acquir Immune Defic Syndr. 2019-9-1

[9]
Ryan White HIV/AIDS program recipients more likely than non-recipients to be retained in care using six different retention measures.

AIDS Care. 2020-1

[10]
Brief Report: Clinical Outcomes of Young Black Men Receiving HIV Medical Care in the United States, 2009-2014.

J Acquir Immune Defic Syndr. 2019-5-1

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