Su Y T, Tang J X, Li S C, Li S J
Department of General Surgery, Huadong Hospital, Fudan University, Shanghai 200040, China.
Zhonghua Wai Ke Za Zhi. 2023 Jun 1;61(6):493-497. doi: 10.3760/cma.j.cn112139-20230221-00078.
To investigate the factors influencing small intestinal ischemia in elderly patients with incarcerated hernia. The clinical data of 105 elderly patients admitted for surgical procedures of incarcerated hernia at Department of General Surgery, Huadong Hospital between January 2014 and December 2021 were retrospectively analyzed. There were 60 males and 45 females, aged (86.1±4.3) years (range: 80 to 96 years). They were divided into normal group (=55) and ischemic group (=50) according to intraoperative intestinal canal condition. The test, test and Fisher's exact probability method were used for the univariate analysis of the factors that influence intestinal ischemia in patients, and Logistic regression was used for multifactorial analysis. In all patients, 18 patients (17.1%) had irreversible intestinal ischemia with bowel resection. Six patients died within 30 days, 3 cases from severe abdominal infection, 2 cases from postoperative exacerbation of underlying cardiac disease, and 1 case from respiratory failure due to severe pulmonary infection. The results of the univariate analysis showed that there were differences in gender, history of intussusception, duration of previous hernia, white blood cell count, neutrophil percentage, C-reactive protein, type of incarcerated hernia, and preoperative intestinal obstruction between the two groups (all <0.05). The Logistic regression results showed that the short time to the previous hernia (=0.892, 95% 0.872 to 0.962, =0.003), high C-reactive protein (=1.022, 95% 1.007 to 1.037, =0.003), non-indirect incarcerated hernia (=10.571, 95% 3.711 to 30.114, <0.01) and preoperative intestinal obstruction (=6.438, 95% 1.762 to 23.522, =0.005) were independent risk factors for the development of intestinal ischemia in elderly patients with incarcerated hernia. The short duration of the previous hernia, the high values of C-reactive proteins, the non-indirect incarcerated hernia, and the preoperative bowel obstruction are influencing factors for bowel ischemia in elderly patients with incarcerated hernia. A timely operation is necessary to reduce the incidence of intestinal necrosis and improve the prognosis.
探讨老年嵌顿疝患者小肠缺血的影响因素。回顾性分析2014年1月至2021年12月在华东医院普通外科接受嵌顿疝手术治疗的105例老年患者的临床资料。其中男性60例,女性45例,年龄(86.1±4.3)岁(范围:80至96岁)。根据术中肠道情况分为正常组(n = 55)和缺血组(n = 50)。采用t检验、χ²检验和Fisher确切概率法对影响患者肠道缺血的因素进行单因素分析,采用Logistic回归进行多因素分析。所有患者中,18例(17.1%)发生不可逆性肠缺血并行肠切除。6例患者在30天内死亡,3例死于严重腹腔感染,2例死于术后基础心脏病加重,1例死于严重肺部感染导致的呼吸衰竭。单因素分析结果显示,两组在性别、肠套叠病史、既往疝持续时间、白细胞计数、中性粒细胞百分比、C反应蛋白、嵌顿疝类型和术前肠梗阻方面存在差异(均P<0.05)。Logistic回归结果显示,既往疝持续时间短(β = 0.892,95%CI 0.872至0.962,P = 0.003)、C反应蛋白高(β = 1.022,95%CI 1.007至1.037,P = 0.003)、非间接性嵌顿疝(β = 10.571,95%CI 3.711至30.114,P<0.01)和术前肠梗阻(β = 6.438,95%CI 1.762至23.522,P = 0.005)是老年嵌顿疝患者发生肠道缺血的独立危险因素。既往疝持续时间短、C反应蛋白值高、非间接性嵌顿疝和术前肠梗阻是老年嵌顿疝患者肠道缺血的影响因素。及时手术对于降低肠坏死发生率和改善预后很有必要。