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益生菌作为伤口愈合剂的作用:全面观察。

The role of probiotics as wound healers: an overall view.

机构信息

Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam-603103, Chennai, Tamil Nadu, India.

出版信息

J Wound Care. 2023 May 2;32(5):318-328. doi: 10.12968/jowc.2023.32.5.318.

Abstract

A wound is an injury to the skin or damage to the body tissue. The healing process differs between various kinds of wounds. Treatment of hard-to-heal (chronic) wounds becomes challenging for healthcare practitioners, especially if patients have underlying health complications such as diabetes. Infection of wounds is another factor that interferes with the healing process and extends its duration. Active research is being conducted into the development of advanced wound dressing technologies. These wound dressings are intended to manage the exudate, reduce bacterial infection and speed up the healing process. Probiotics have been receiving much attention because of their potential application in the clinical field, especially in diagnostics and treatment strategies of various infectious and non-infectious diseases. The host immune-modulatory response and antimicrobial activity of probiotics are expanding their role in the development of improved wound dressing technology.

摘要

伤口是皮肤损伤或身体组织损伤。不同类型的伤口的愈合过程不同。对于医疗保健从业者来说,治疗难以愈合(慢性)伤口具有挑战性,特别是如果患者有潜在的健康并发症,如糖尿病。伤口感染是另一个干扰愈合过程并延长其持续时间的因素。目前正在积极研究开发先进的伤口敷料技术。这些伤口敷料旨在控制渗出物,减少细菌感染并加速愈合过程。由于益生菌在临床领域的潜在应用,特别是在各种感染性和非传染性疾病的诊断和治疗策略中,它们受到了广泛关注。益生菌的宿主免疫调节反应和抗菌活性正在扩大其在改进伤口敷料技术开发中的作用。

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