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CT 引导下经皮肺穿刺活检细胞学检查在 COVID-19 大流行期间用于肺癌诊断:我们的经验教训。

CT Scan-Guided Fine Needle Aspiration Cytology for Lung Cancer Diagnosis through the COVID-19 Pandemic: What We Have Learned.

机构信息

Department of Internal Medicine and Medical Therapeutics, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.

Unit of Respiratory Diseases, Cardio-Thoraco-Vascular Department, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.

出版信息

Tomography. 2023 Mar 31;9(2):759-767. doi: 10.3390/tomography9020061.

Abstract

BACKGROUND AND RATIONALE

Novel coronavirus-related disease (COVID-19) has profoundly influenced hospital organization and structures worldwide. In Italy, the Lombardy Region, with almost 17% of the Italian population, rapidly became the most severely affected area since the pandemic beginning. The first and the following COVID-19 surges significantly affected lung cancer diagnosis and subsequent management. Much data have been already published regarding the therapeutic repercussions whereas very few reports have focused on the consequences of the pandemic on diagnostic procedures.

METHODS

We, here, would like to analyze data of novel lung cancer diagnosis performed in our Institution in Norther Italy where we faced the earliest and largest outbreaks of COVID-19 in Italy.

RESULTS

We discuss, in detail, the strategies developed to perform biopsies and the safe pathways created in emergency settings to protect lung cancer patients in subsequent therapeutic phases. Quite unexpectedly, no significant differences emerged between cases enrolled during the pandemic and those before, and the two populations were homogeneous considering the composition and diagnostic and complication rates.

CONCLUSIONS

By pointing out the role of multidisciplinarity in emergency contexts, these data will be of help in the future for designing tailored strategies to manage lung cancer in a real-life setting.

摘要

背景和原理

新型冠状病毒相关疾病(COVID-19)深刻影响了全球医院的组织和结构。在意大利,伦巴第大区(人口占全国 17%)自疫情开始以来迅速成为受影响最严重的地区。第一次和随后的 COVID-19 浪潮对肺癌的诊断和后续管理产生了重大影响。已经发表了大量关于治疗影响的数据,而很少有报告关注大流行对诊断程序的影响。

方法

在这里,我们希望分析在意大利北部的我们机构中进行的新型肺癌诊断的数据,我们在那里面临了意大利最早和最大的 COVID-19 疫情爆发。

结果

我们详细讨论了为进行活检而制定的策略,以及在紧急情况下创建的安全途径,以保护后续治疗阶段的肺癌患者。出人意料的是,在大流行期间和之前登记的病例之间没有出现显著差异,而且这两个群体在构成、诊断和并发症发生率方面是同质的。

结论

通过指出在紧急情况下多学科的作用,这些数据将有助于未来设计针对真实环境中肺癌管理的定制策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d08/10143076/0f965229beb2/tomography-09-00061-g001.jpg

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