Moztarzadeh Omid, Jamshidi Mohammad Behdad, Sargolzaei Saleh, Jamshidi Alireza, Baghalipour Nasimeh, Malekzadeh Moghani Mona, Hauer Lukas
Department of Stomatology, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.
Department of Anatomy, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.
Bioengineering (Basel). 2023 Apr 7;10(4):455. doi: 10.3390/bioengineering10040455.
Medical digital twins, which represent medical assets, play a crucial role in connecting the physical world to the metaverse, enabling patients to access virtual medical services and experience immersive interactions with the real world. One serious disease that can be diagnosed and treated using this technology is cancer. However, the digitalization of such diseases for use in the metaverse is a highly complex process. To address this, this study aims to use machine learning (ML) techniques to create real-time and reliable digital twins of cancer for diagnostic and therapeutic purposes. The study focuses on four classical ML techniques that are simple and fast for medical specialists without extensive Artificial Intelligence (AI) knowledge, and meet the requirements of the Internet of Medical Things (IoMT) in terms of latency and cost. The case study focuses on breast cancer (BC), the second most prevalent form of cancer worldwide. The study also presents a comprehensive conceptual framework to illustrate the process of creating digital twins of cancer, and demonstrates the feasibility and reliability of these digital twins in monitoring, diagnosing, and predicting medical parameters.
代表医疗资产的医学数字孪生在将物理世界与元宇宙连接起来方面发挥着关键作用,使患者能够获得虚拟医疗服务并体验与现实世界的沉浸式互动。一种可以使用这项技术进行诊断和治疗的严重疾病是癌症。然而,将此类疾病数字化以用于元宇宙是一个高度复杂的过程。为了解决这个问题,本研究旨在使用机器学习(ML)技术创建用于诊断和治疗目的的实时、可靠的癌症数字孪生。该研究专注于四种经典的ML技术,这些技术对于没有广泛人工智能(AI)知识的医学专家来说简单快速,并且在延迟和成本方面满足医疗物联网(IoMT)的要求。案例研究聚焦于乳腺癌(BC),它是全球第二大常见癌症形式。该研究还提出了一个全面的概念框架来说明创建癌症数字孪生的过程,并展示了这些数字孪生在监测、诊断和预测医学参数方面的可行性和可靠性。