Pôle Cancérologie et Spécialités Médicales - Centre Hospitalier de Valenciennes, France; Univ. Lille, CNRS, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, F-59000, Lille, France; Human and Social Sciences Department - Centre Léon Bérard, Lyon, France.
Human and Social Sciences Department - Centre Léon Bérard, Lyon, France.
Eur J Oncol Nurs. 2023 Jun;64:102324. doi: 10.1016/j.ejon.2023.102324. Epub 2023 Mar 11.
The existing literature shows a significant impact of cancer on caregivers' quality of life (QoL) and divergent results according to associated factors. To better understand the experience of cancer patients' caregivers, the present study aimed at comparing caregivers' QoL according to cancer care pathway and type of cancer, and at identifying the factors associated with their QoL.
Caregivers were included in the study either during chemotherapy or follow-up to assess their QoL (CARGOQoL), unmet supportive care needs (SCNS-P&C), and anxiety and depression levels (HADS). CARGOQoL scores were then compared using ANOVA or Mann-Whitney non-parametric tests (objective 1). Based on univariate analyses, a multivariate analysis of covariance or linear regression model was performed for each CARGOQoL dimension (objective 2).
Among 583 participants (57.29% included during the follow-up phase), 523 completed the questionnaires. There was no effect of treatment phase and little effect of cancer site or disease stage on caregivers' QoL. Although significant factors associated with caregivers' QoL varied according to the dimensions assessed, the main associated factors were psychological experience (p < 0.05), satisfaction with the patient's care and supportive care needs (p < 0.01), and age of the patient or caregiver (p < 0.005).
This study shows the necessity to support caregivers during both active treatment and follow-up. It highlights the crucial role of emotional distress, supportive care and age in caregivers' QoL, regardless of the patients' oncological status.
现有文献表明，癌症对照顾者的生活质量（QoL）有重大影响，但根据相关因素的不同，结果也存在差异。为了更好地了解癌症患者照顾者的体验，本研究旨在根据癌症护理途径和癌症类型比较照顾者的 QoL，并确定与其 QoL 相关的因素。
研究纳入了接受化疗或随访的照顾者，以评估他们的生活质量（CARGOQoL）、未满足的支持性护理需求（SCNS-P&C）以及焦虑和抑郁水平（HADS）。使用 ANOVA 或 Mann-Whitney 非参数检验比较 CARGOQoL 评分（目标 1）。基于单变量分析，对每个 CARGOQoL 维度进行多元协方差分析或线性回归模型（目标 2）。
在 583 名参与者中（57.29%在随访阶段纳入），有 523 名完成了问卷。治疗阶段和癌症部位或疾病阶段对照顾者的 QoL 没有影响。尽管与照顾者 QoL 相关的显著因素根据评估的维度而有所不同，但主要相关因素是心理体验（p<0.05）、对患者护理和支持性护理需求的满意度（p<0.01）以及患者或照顾者的年龄（p<0.005）。
本研究表明，在积极治疗和随访期间都需要支持照顾者。它强调了情感困扰、支持性护理和年龄在照顾者 QoL 中的关键作用，而与患者的肿瘤状态无关。
