Department of Pharmacy, University of "G. d'Annunzio" Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy.
Int J Mol Sci. 2023 May 3;24(9):8194. doi: 10.3390/ijms24098194.
The use of large sized materials in drug delivery raises several challenges, including in vivo stability, poor bioavailability/solubility/absorption, and issues with target-specific delivery, in addition to the side effects of the delivered drugs [...].
大尺寸药物递送材料的使用带来了一些挑战,包括体内稳定性、生物利用度/溶解度/吸收率差以及靶向递送问题,此外还存在所递送药物的副作用[...]。