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超声乳化术对带功能性引流管眼内眼压的影响。

Effect of Phacoemulsification on Intraocular Pressure in Eyes with Functioning Tube Shunts.

作者信息

Shamseldin Shalaby Wesam, Patel Sonali, S Lam Sophia, Ganjei Allen, Garg Shukla Aakriti, Kolomeyer Natasha, Lee Daniel, Jay Katz L, R Moster Marlene, Myers Jonathan, Razeghinejad Reza

机构信息

Wills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA.

Tanta Medical School, Tanta University, Tanta, Gharbia, Egypt.

出版信息

J Ophthalmic Vis Res. 2023 Apr 19;18(2):150-156. doi: 10.18502/jovr.v18i2.13180. eCollection 2023 Apr-Jun.

Abstract

PURPOSE

To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in eyes with functioning tube shunts.

METHODS

This was a retrospective chart review of primary open-angle glaucoma (POAG) patients with a functioning tube who underwent phacoemulsification and had 24 months of follow-up. The primary end point was defined as surgical failure (IOP 21 mmHg) at month 24, progression to no light perception (NLP) vision, glaucoma reoperation, or implant removal. Surgical failure defined as IOP 18 and 15 mmHg, changes in visual acuity (VA), IOP, and number of medications were assessed.

RESULTS

Twenty-seven eyes of 27 patients with moderate or severe POAG were included. The mean age of the patients was 64.2 10.8 years. The interval between the tube shunt and phacoemulsification was 28.8 25.0 months. At the end of the study, four (14.8%) eyes met the failure criteria; the average time to failure was 9.3 3.8 months. The causes of failure were high IOP in two (50.0%) and glaucoma reoperation in two (50.0%) eyes; however, no eyes progressed to NLP vision. Surgical failure defined as IOP 18 and 15 mmHg showed an increasing failure rate (18.5% and 48.5%, respectively).Themean IOP and medications number remained stable at month 24 compared to baseline ( = 0.131 and = 0.302, respectively). Initially, VA showed improvement, with the greatest improvement at 6 months ( = 0.001), but at 24 months the improvement was no longer significant ( = 0.430).

CONCLUSION

Phacoemulsification in patients with functioning tubes did not change the mean IOP in most of the patients (86.2%); the number of medications also did not increase.

摘要

目的

评估超声乳化术对具有功能性引流管的眼睛的眼压(IOP)的影响。

方法

这是一项对接受超声乳化术并进行了24个月随访的原发性开角型青光眼(POAG)且带有功能性引流管的患者的回顾性病历审查。主要终点定义为在第24个月时手术失败(眼压≥21 mmHg)、进展为无光感(NLP)视力、青光眼再次手术或植入物取出。将手术失败定义为眼压≥18和≥15 mmHg,评估视力(VA)、眼压和药物数量的变化。

结果

纳入了27例中重度POAG患者的27只眼睛。患者的平均年龄为64.2±10.8岁。引流管与超声乳化术之间的间隔为28.8±25.0个月。在研究结束时,4只(14.8%)眼睛符合失败标准;失败的平均时间为9.3±3.8个月。失败原因是2只(50.0%)眼睛眼压高,2只(50.0%)眼睛进行了青光眼再次手术;然而,没有眼睛进展为无光感视力。将手术失败定义为眼压≥18和≥15 mmHg时,失败率呈上升趋势(分别为18.5%和48.5%)。与基线相比,第24个月时平均眼压和药物数量保持稳定(分别为P = 0.131和P = 0.302)。最初,视力有所改善,在6个月时改善最大(P = 0.001),但在24个月时改善不再显著(P = 0.430)。

结论

对于具有功能性引流管的患者,超声乳化术在大多数患者(86.2%)中并未改变平均眼压;药物数量也未增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7796/10172799/6a338d4c4678/jovr-18-150-g001.jpg

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