Department of Photonics, National Cheng Kung University, Tainan 70101, Taiwan.
Department of Chemical Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
Chem Commun (Camb). 2023 May 23;59(42):6339-6342. doi: 10.1039/d3cc00733b.
3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 10 CFU cm for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.
采用单宁酸(化学胶和还原剂)在聚乳酸微针上自组装金纳米粒子,制备了 3D SERS 微针,用于深入的化学和生物分子分析,小分子的 LOD 值低于 200 ppb,细菌的 LOD 值低于 10 CFU cm。MB/Au 微针用于光动力学治疗,通过 SERS 监测光敏剂降解。