用于治疗肺癌的创新性侵入性局部区域技术。

Innovative Invasive Loco-Regional Techniques for the Treatment of Lung Cancer.

作者信息

Claes Erik, Wener Reinier, Neyrinck Arne P, Coppens Axelle, Van Schil Paul E, Janssens Annelies, Lapperre Thérèse S, Snoeckx Annemiek, Wen Wen, Voet Hanne, Verleden Stijn E, Hendriks Jeroen M H

机构信息

ASTARC (Antwerp Surgical Training, Anatomy and Research Centre), University Hospital Antwerp, Drie Eikenstraat 655, 2650 Edegem, Belgium.

Department of Thoracic and Vascular Surgery, University Hospital Antwerp, Drie Eikenstraat 655, 2650 Edegem, Belgium.

出版信息

Cancers (Basel). 2023 Apr 11;15(8):2244. doi: 10.3390/cancers15082244.

DOI:10.3390/cancers15082244

PMID:37190172

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10136896/

Abstract

Surgical resection is still the standard treatment for early-stage lung cancer. A multimodal treatment consisting of chemotherapy, radiotherapy and/or immunotherapy is advised for more advanced disease stages (stages IIb, III and IV). The role of surgery in these stages is limited to very specific indications. Regional treatment techniques are being introduced at a high speed because of improved technology and their possible advantages over traditional surgery. This review includes an overview of established and promising innovative invasive loco-regional techniques stratified based on the route of administration, including endobronchial, endovascular and transthoracic routes, a discussion of the results for each method, and an overview of their implementation and effectiveness.

摘要

手术切除仍是早期肺癌的标准治疗方法。对于更晚期的疾病阶段（IIb期、III期和IV期），建议采用化疗、放疗和/或免疫治疗的多模式治疗。手术在这些阶段的作用仅限于非常特定的适应症。由于技术的改进及其相对于传统手术可能具有的优势，区域治疗技术正在迅速引入。本综述包括基于给药途径分层的既定和有前景的创新侵入性局部区域技术的概述，包括支气管内、血管内和经胸途径，对每种方法的结果进行讨论，以及对其实施情况和有效性的概述。