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干燥综合征。

Sjögren's syndrome.

机构信息

3rd Department of Rheumatology, National Institute of Rheumatology and Physiotherapy, Frankel Leó út 27-29, Budapest, 1023, Hungary.

Department of Medicine, McMaster University, Hamilton, ON, L8P 1H6, Canada.

出版信息

Inflammopharmacology. 2024 Feb;32(1):37-43. doi: 10.1007/s10787-023-01222-z. Epub 2023 May 17.

Abstract

Sjögren's syndrome (SS) is characterised as keratoconjunctivitis sicca (dry eyes), xerostomia (dry mouth) commonly associated with salivary gland enlargement, and is referred to as Primary Sjögren's syndrome. It is known as Secondary Sjögren's syndrome when it occurs in patients, with connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, polyarthritis nodosa, polymyositis, and systemic sclerosis. SS has also been associated with chronic graft-versus-host disease after allogeneic bone marrow transplantation, human immunodeficiency syndrome (AIDS), hepatitis C infection (HCV), chronic biliary cirrhosis, neoplastic and myeloplastic syndromes, fibromyalgia, and chronic fatigue syndrome.

摘要

干燥综合征(SS)的特征为眼干(干眼症)、口干(干燥性口炎),常伴有唾液腺肿大,称为原发性干燥综合征。当发生于结缔组织病患者,如类风湿关节炎、系统性红斑狼疮、多发性关节炎、多发性肌炎和系统性硬化症时,称为继发性干燥综合征。SS 还与异基因骨髓移植后的慢性移植物抗宿主病、人类免疫缺陷病毒(AIDS)、丙型肝炎病毒(HCV)感染、慢性胆汁性肝硬化、肿瘤和骨髓增生性综合征、纤维肌痛和慢性疲劳综合征有关。

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