Awuah Alfred, Shah Punit Jitendra, Tariq Farheen
Houston Methodist Hospital, Houston, TX, USA.
Houston Methodist Sugar Land Hospital, Sugar Land, TX, USA.
Hosp Pharm. 2023 Jun;58(3):259-262. doi: 10.1177/00185787221142471. Epub 2022 Dec 13.
Artesunate is an effective and first-line therapy option in patients with severe malaria caused by species. Among adverse effects of the drug is a phenomenon of delayed hemolysis. This usually occurs at least 7 days after initiation of therapy, and is characterized by reductions in hemoglobin and haptoglobin and an increase in lactate dehydrogenase. Here, we report an instance of delayed hemolysis in a patient probably attributed to parenteral artesunate therapy.
青蒿琥酯是由该物种引起的严重疟疾患者的一种有效且一线的治疗选择。该药物的不良反应之一是延迟溶血现象。这通常发生在治疗开始后至少7天,其特征是血红蛋白和触珠蛋白降低以及乳酸脱氢酶升高。在此,我们报告一例可能归因于青蒿琥酯胃肠外给药治疗的延迟溶血病例。