Department of Health Policy Science, Graduate School of Medical Science, Yamagata University, Yamagata, Japan.
Department of International and Community Oral Health, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Eur J Pain. 2023 Sep;27(8):973-980. doi: 10.1002/ejp.2139. Epub 2023 May 25.
This study aimed to assess the impacts of smoking cessation and resumption over 4 years on the risk of back pain at the 6-year follow-up among older adults in England.
We analysed 6467 men and women aged ≥50 years in the English Longitudinal Study of Aging. Self-reported smoking status, assessed in waves 4 (2008-2009) and 6 (2012-2013), was used as exposure for the study, whereas self-reported back pain of moderate or severe intensity, assessed in wave 7 (2014-2015), was used as the outcome. A targeted minimum loss-based estimator was used with longitudinal modified treatment policies to adjust for baseline and time-varying covariates.
Regarding the estimation of the effects of changes in smoking status on the risk of back pain, during the follow-up, individuals who resumed smoking within 4 years had a higher risk of back pain than those who avoided smoking for over 4 years, and the relative risk (RR) (95% confidence interval [CI]) was 1.536 (1.214-1.942). Regarding the estimation of effects of smoking cessation on the risk of back pain, smoking cessation over 4 years was associated with a significantly lower risk of back pain, as indicated by the originally observed data, and the RR (95% CI) was 0.955 (0.912-0.999).
Older adults who avoided smoking for over 4 years had a lower risk of back pain. However, those who resumed smoking within 4 years had a higher risk of back pain.
Older adults who avoided smoking for over 4 years had a lower risk of back pain. However, those who resumed smoking within 4 years had a higher risk of back pain. Our study data suggest the importance of maintaining smoking cessation to reduce the risk of back pain in the older population.
本研究旨在评估在英格兰,4 年内吸烟的开始和停止对 6 年后老年人背痛风险的影响。
我们分析了英国老龄化纵向研究中 6467 名年龄≥50 岁的男性和女性。使用第 4 波(2008-2009 年)和第 6 波(2012-2013 年)评估的自我报告吸烟状况作为研究暴露因素,而第 7 波(2014-2015 年)评估的中度或重度背痛自我报告则作为结果。使用纵向修正治疗策略的有针对性最小损失估计器来调整基线和时变协变量。
在评估吸烟状况变化对背痛风险的影响方面,在随访期间,4 年内重新开始吸烟的个体比超过 4 年内避免吸烟的个体患背痛的风险更高,相对风险(RR)(95%置信区间[CI])为 1.536(1.214-1.942)。在评估戒烟对背痛风险的影响方面,4 年内戒烟与背痛风险显著降低相关,这是根据原始观察数据得出的,RR(95%CI)为 0.955(0.912-0.999)。
4 年内避免吸烟的老年人背痛风险较低。然而,4 年内重新开始吸烟的人患背痛的风险较高。
4 年内避免吸烟的老年人背痛风险较低。然而,4 年内重新开始吸烟的人患背痛的风险较高。我们的研究数据表明,为了降低老年人群背痛的风险,保持戒烟非常重要。