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鼻间隔穿孔的内镜修复结果。

Outcome of Endoscopic Repair of Nasal Septal Perforation.

机构信息

Department of Otolaryngology, West Virginia University, Morgantown, WV, USA.

American University of Beirut, Beirut, Lebanon.

出版信息

Ann Otol Rhinol Laryngol. 2023 Dec;132(12):1617-1620. doi: 10.1177/00034894231176610. Epub 2023 May 28.

Abstract

INTRODUCTION

The anterior ethmoidal artery (AEA) flap has been demonstrated to be a reliable option for endoscopic repair of symptomatic nasal septal perforations. The purpose of this study is to study the outcome of this technique.

METHODS

A retrospective case series of all consecutive patients who underwent repair of nasal septal perforation utilizing the AEA flap among 2 institutions from August 2020 to July of 2022 was conducted. Demographics and comorbidities were collected preoperatively and postoperatively. The main outcome of this study was to identify the risk factors for surgical failure.

RESULTS

Forty-one patients were included. Mean perforation size was 2.2 cm (range 0.5-4.5 cm). Mean age was 42.5 years (range 14-65 years), 53.6% were female, 39% were active smokers, mean body-mass-index (BMI) was 31.9 (range 19.1-45.5), 20% with history of CRS and 31.7% had diabetes mellitus (DM). Etiologies of the perforation included idiopathic (n = 12), iatrogenic (n = 13), intranasal drug use (n = 7), trauma (n = 6), and secondary to tumor resection (n = 3). Overall success rate for complete closure was 73.2%. Active smoking, history of intranasal drug use, and DM were significantly associated with surgical failure (72.7%vs 26.7%,  = .007; 36.4%vs 10%,  = .047; and 63.6%vs 20%,  = .008 respectively).

CONCLUSION

The endoscopic AEA flap is a reliable technique for closure of nasal septal perforation. It may not work when the etiology is intranasal drug use. Close attention to diabetes and smoking status is also needed.

摘要

简介

前筛动脉(AEA)皮瓣已被证明是内镜修复症状性鼻中隔穿孔的可靠选择。本研究旨在研究该技术的结果。

方法

对 2020 年 8 月至 2022 年 7 月期间在 2 个机构接受 AEA 皮瓣修复鼻中隔穿孔的所有连续患者进行回顾性病例系列研究。收集术前和术后的人口统计学和合并症数据。本研究的主要结果是确定手术失败的风险因素。

结果

共纳入 41 例患者。平均穿孔大小为 2.2cm(范围 0.5-4.5cm)。平均年龄为 42.5 岁(范围 14-65 岁),53.6%为女性,39%为主动吸烟者,平均体重指数(BMI)为 31.9(范围 19.1-45.5),20%有 CRS 病史,31.7%有糖尿病(DM)。穿孔的病因包括特发性(n=12)、医源性(n=13)、鼻内药物使用(n=7)、创伤(n=6)和继发于肿瘤切除(n=3)。完全闭合的总体成功率为 73.2%。吸烟、鼻内药物使用史和糖尿病与手术失败显著相关(72.7%比 26.7%,  = .007;36.4%比 10%,  = .047;63.6%比 20%,  = .008)。

结论

内镜 AEA 皮瓣是闭合鼻中隔穿孔的可靠技术。当病因是鼻内药物使用时,它可能不起作用。还需要密切关注糖尿病和吸烟状况。

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