University Hospital Llandough, Penarth, Cardiff, UK.
Adelphi Real World, Macclesfield, UK.
Int J Obes (Lond). 2023 Aug;47(8):750-757. doi: 10.1038/s41366-023-01325-1. Epub 2023 May 31.
Obesity-related complications (ORCs), such as type 2 diabetes (T2D) and cardiovascular disease, contribute considerably to the clinical and economic impacts of obesity. To obtain a holistic overview of health and weight management attempts for people with obesity in Europe, we designed the cross-sectional RESOURCE survey to collect data on comorbidities, healthcare resource use (HCRU) and weight loss strategies from people with obesity in France, Germany, Italy, Spain, Sweden and the UK.
Adults (≥18 years old) with self-reported body mass index (BMI) ≥30 kg/m who reported interacting with primary or secondary healthcare services in the past 12 months, but had not been pregnant during this time, were recruited from an existing consumer research panel. All data were self-reported via an online survey (May-June 2021). Weight changes over the past year were calculated from participants' estimated weights.
Of the 1850 participants in the survey, 26.3% reported that they had ≥3 ORCs from a set of 15 conditions of interest. The most frequently reported ORCs were hypertension (39.3% of participants), dyslipidaemia (22.8%) and T2D (17.5%). Participants in obesity class III (BMI 40 to <70 kg/m) were more likely to report multiple ORCs than those in lower obesity classes. The presence of multiple ORCs was linked to various types of HCRU, including a significantly increased chance of reporting hospitalization in the past year. Most participants (78.6%) had attempted to lose weight in the past year, but of those who also reported estimated weight changes, 73.4% had not experienced clinically meaningful weight loss of ≥5%.
ORCs are common in people with obesity, and are linked to increased HCRU. Together with the low reported success rate of weight loss attempts, this highlights an unmet need in Europe for enhanced weight management support for people with obesity.
肥胖相关并发症(ORCs),如 2 型糖尿病(T2D)和心血管疾病,对肥胖的临床和经济影响很大。为了全面了解欧洲肥胖人群的健康和体重管理尝试,我们设计了横断面研究 RESOURCE 调查,以收集来自法国、德国、意大利、西班牙、瑞典和英国肥胖人群的合并症、医疗保健资源使用(HCRU)和减肥策略的数据。
从现有的消费者研究小组中招募了过去 12 个月内自我报告身体质量指数(BMI)≥30kg/m2 且在此期间未怀孕但与初级或二级医疗保健服务有过互动的成年人(≥18 岁)。所有数据均通过在线调查(2021 年 5 月至 6 月)自报。根据参与者估计的体重计算过去一年的体重变化。
在调查的 1850 名参与者中,26.3%报告他们有 15 种感兴趣疾病中的≥3 种 ORCs。报告的最常见 ORCs 是高血压(39.3%的参与者)、血脂异常(22.8%)和 T2D(17.5%)。肥胖等级 III(BMI40 至<70kg/m)的参与者比低肥胖等级的参与者更有可能报告多种 ORCs。多种 ORCs 的存在与各种类型的 HCRU 相关,包括过去一年报告住院的可能性显著增加。大多数参与者(78.6%)在过去一年中曾试图减肥,但在报告估计体重变化的参与者中,73.4%没有经历过≥5%的临床显著减肥。
ORCs 在肥胖人群中很常见,并且与 HCRU 的增加有关。加上减肥尝试的低报告成功率,这突显了欧洲肥胖人群对增强肥胖管理支持的未满足需求。