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心包切除术的麻醉管理。一项病例系列研究。

Anesthesia management for pericardiectomy- a case series study.

机构信息

Department of Anesthesiology, Peking University International Hospital, Beijing, China.

Chinese Academy of Medical Sciences, Fuwai Hospital, Beijing, China.

出版信息

BMC Anesthesiol. 2023 Jun 1;23(1):191. doi: 10.1186/s12871-023-02155-4.

Abstract

BACKGROUND

Constrictive pericarditis (CP) is an uncommon disease that limits both cardiac relaxation and contraction. Patients often present with right-sided heart failure as the pericardium thickens and impedes cardiac filling. Pericardiectomy is the treatment of choice for improving hemodynamics in CP patients; however, the procedure carries a high morbidity and mortality, and the anesthetic management can be challenging. Acute heart failure, bleeding and arrhythmias are all concerns postoperatively.

METHODS

After IRB approval, we performed the retrospective analysis of 66 consecutive patients with CP who underwent pericardiectomy from July 2018 to May 2022.

RESULTS

Most patients had significant preoperative comorbidities, including congestive hepatopathy (75.76%), New York Heart Association Type III/IV heart failure (59.09%) and atrial fibrillation (51.52%). Despite this, 75.76% of patients were extubated within the first 24 h and all but 2 of the patients survived to discharge (96.97%).

CONCLUSIONS

Anesthetic management, including a thorough understanding of the pathophysiology of CP, the use of advanced monitoring and transesophageal echocardiography (TEE) guidance, all played an important role in patient outcomes.

摘要

背景

缩窄性心包炎(CP)是一种罕见的疾病,限制了心脏的舒张和收缩。随着心包增厚并阻碍心脏充盈,患者常出现右侧心力衰竭。心包切除术是改善 CP 患者血液动力学的首选治疗方法;然而,该手术具有较高的发病率和死亡率,麻醉管理具有挑战性。急性心力衰竭、出血和心律失常都是术后的关注点。

方法

在获得机构审查委员会批准后,我们对 2018 年 7 月至 2022 年 5 月期间接受心包切除术的 66 例 CP 连续患者进行了回顾性分析。

结果

大多数患者术前合并症严重,包括充血性肝疾病(75.76%)、纽约心脏协会心功能 III/IV 级(59.09%)和心房颤动(51.52%)。尽管如此,75.76%的患者在 24 小时内拔管,除 2 例患者外,所有患者均存活至出院(96.97%)。

结论

麻醉管理,包括对 CP 病理生理学的深入了解、使用先进的监测和经食管超声心动图(TEE)指导,都对患者的结局起着重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ce/10233876/12ad14d8535b/12871_2023_2155_Fig1_HTML.jpg

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