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头颈部癌症中的下颌骨重建:何为金标准?

Mandibular reconstruction in head and neck cancer: which is the gold standard?

机构信息

Young Confederation of European ORL-HNS, Y-CEORL-HNS, Vienna, Austria.

Head and Neck Department, University Hospital of Verona, Verona, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2023 Sep;280(9):3953-3965. doi: 10.1007/s00405-023-08050-5. Epub 2023 Jun 3.

Abstract

INTRODUCTION

The aim of this study is to perform a systematic review to compare the outcomes of the different surgical options for mandibular reconstruction in head and neck cancer.

MATERIAL AND METHODS

93 articles were selected. Four groups were identified: titanium plate without flaps, titanium plate covered by soft tissue flap, bone tissue flaps and double flaps. We compared patients' characteristics, site of mandibulectomy, type of reconstruction and complications.

RESULTS

4697 patients were reported. The groups were not homogeneous regarding the type of defect and the treatment history. A significant difference in terms of post-operative complications was found between group 1 and group 2 (p < 0.00001), and between group 2 and group 3 (p < 0.00001). Total complications rate for group 4 was significantly higher when compared to group 3 (p < 0.00001), but no significant difference was found with group 2.

CONCLUSION

These results suggest that mandibular reconstruction using a microvascular bone flap is the best surgical option in patients without significant comorbidities.

摘要

简介

本研究旨在进行系统评价,比较头颈部癌症下颌骨重建的不同手术选择的结果。

材料和方法

共选择了 93 篇文章。确定了四个组:无皮瓣钛板、软组织瓣覆盖的钛板、骨组织瓣和双瓣。我们比较了患者特征、下颌骨切除术部位、重建类型和并发症。

结果

报告了 4697 例患者。各组在缺陷类型和治疗史方面均不一致。组 1 和组 2(p<0.00001)以及组 2 和组 3(p<0.00001)之间术后并发症存在显著差异。与组 3 相比,组 4 的总并发症发生率明显更高(p<0.00001),但与组 2 相比无显著差异。

结论

这些结果表明,在没有明显合并症的患者中,使用微血管骨瓣进行下颌骨重建是最佳的手术选择。

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