Center for Economic and Social Research, University of Southern California, Los Angeles.
RAND Corporation, Santa Monica, California.
JAMA Pediatr. 2023 Aug 1;177(8):847-855. doi: 10.1001/jamapediatrics.2023.1329.
Despite strong evidence linking place and obesity risk, the extent to which this link is causal or reflects sorting into places is unclear.
To examine the association of place with adolescents' obesity and explore potential causal pathways, such as shared environments and social contagion.
DESIGN, SETTING, AND PARTICIPANTS: This natural experiment study used the periodic reassignment of US military servicemembers to installations as a source of exogenous variation in exposure to difference places to estimate the association between place and obesity risk. The study analyzed data from the Military Teenagers Environments, Exercise, and Nutrition Study, a cohort of adolescents in military families recruited from 2013 through 2014 from 12 large military installations in the US and followed up until 2018. Individual fixed-effects models were estimated that examined whether adolescents' exposure to increasingly obesogenic places over time was associated with increases in body mass index (BMI) and probability of overweight or obesity. These data were analyzed from October 15, 2021, through March 10, 2023.
Adult obesity rate in military parent's assigned installation county was used as a summary measure of all place-specific obesogenic influences.
Outcomes were BMI, overweight or obesity (BMI in the 85th percentile or higher), and obesity (BMI in the 95th percentile or higher). Time at installation residence and off installation residence were moderators capturing the degree of exposure to the county. County-level measures of food access, physical activity opportunities, and socioeconomic characteristics captured shared environments.
A cohort of 970 adolescents had a baseline mean age of 13.7 years and 512 were male (52.8%). A 5 percentage point-increase over time in the county obesity rate was associated with a 0.19 increase in adolescents' BMI (95% CI, 0.02-0.37) and a 0.02-unit increase in their probability of obesity (95% CI, 0-0.04). Shared environments did not explain these associations. These associations were stronger for adolescents with time at installation of 2 years or longer vs less than 2 years for BMI (0.359 vs. 0.046; P value for difference in association = .02) and for probability of overweight or obesity (0.058 vs. 0.007; P value for difference association = .02), and for adolescents who lived off installation vs on installation for BMI (0.414 vs. -0.025; P value for association = .01) and for probability of obesity (0.033 vs. -0.007; P value for association = .02).
In this study, the link between place and adolescents' obesity risk is not explained by selection or shared environments. The study findings suggest social contagion as a potential causal pathway.
尽管有强有力的证据表明地点与肥胖风险之间存在关联,但这种关联是因果关系还是反映了对地点的分类尚不清楚。
研究地点与青少年肥胖之间的关联,并探讨潜在的因果途径,如共同环境和社会传染。
设计、地点和参与者:这项自然实验研究利用美国军人在军事设施之间周期性的重新分配作为暴露于不同地点差异的外生变化的来源,以估计地点与肥胖风险之间的关联。该研究分析了来自军事青少年环境、锻炼和营养研究的数据,这是一个从 2013 年到 2014 年从美国 12 个大型军事设施招募的军人家庭青少年队列,并跟踪至 2018 年。估计了个体固定效应模型,检查了青少年随着时间的推移接触日益肥胖的地方与体重指数(BMI)增加和超重或肥胖的概率增加之间是否存在关联。这些数据于 2021 年 10 月 15 日至 2023 年 3 月 10 日进行了分析。
军人父母所在军事单位所在县的成年人肥胖率被用作所有特定地点肥胖影响的综合衡量标准。
结果是 BMI、超重或肥胖(BMI 处于第 85 百分位或更高)和肥胖(BMI 处于第 95 百分位或更高)。在军事单位居住时间和不在军事单位居住时间是捕获县暴露程度的调节剂。县一级的食物获取、体育活动机会和社会经济特征的衡量标准反映了共同环境。
一个由 970 名青少年组成的队列,基线平均年龄为 13.7 岁,512 名为男性(52.8%)。县肥胖率每增加 5 个百分点,青少年的 BMI 就会增加 0.19(95%CI,0.02-0.37),肥胖的概率就会增加 0.02 个单位(95%CI,0-0.04)。这些关联不能用共同环境来解释。对于在军事单位居住时间为 2 年或以上的青少年,与居住时间少于 2 年的青少年相比,这些关联更强,对于 BMI(0.359 与 0.046;关联差异的 P 值=0.02)和超重或肥胖的概率(0.058 与 0.007;关联差异的 P 值=0.02),对于居住在军事单位以外的青少年,与居住在军事单位的青少年相比,对于 BMI(0.414 与-0.025;关联的 P 值=0.01)和肥胖的概率(0.033 与-0.007;关联的 P 值=0.02),这些关联更强。
在这项研究中,地点与青少年肥胖风险之间的联系不能用选择或共同环境来解释。研究结果表明,社会传染是一个潜在的因果途径。