Department of Oral and Dental Health, Vocational School of Health Services, Artvin Çoruh University, Artvin, Turkey.
Department of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Çoruh University, Artvin, Turkey.
Dent Med Probl. 2023 Apr-Jun;60(2):219-225. doi: 10.17219/dmp/134290.
Dental caries occurs with the release of organic acids from the fermentable carbohydrates metabolized by cariogenic microorganisms. Microbial, genetic, immunological, behavioral, and environmental factors play a role in the development and severity of dental caries.
The aim of the present study was to investigate the possible effects of different mouthwash solutions on dental remineralization.
This in vitro study compared the remineralization capacity of different mouthwash solutions applied topically to the enamel surface. A total of 50 tooth specimens were prepared from the buccal and lingual halves, with 10 teeth in each group: G1 (control); G2 (Listerine®); G3 (Sensodyne®); G4 (Oral B® Pro-Expert); and G5 (DentaSave® Zinc). Remineralization capacity was evaluated in all groups. The one-way analysis of variance (ANOVA) and the paired samples t test were used for statistical analysis, with a p-value <0.05 considered significant.
There were significant differences in the calcium (Ca)/phosphorus (P) atomic percentage (at%) ratio between the demineralized and remineralized dentin (p = 0.001), and between the demineralized and remineralized enamel (p = 0.006). Similarly, there were significant differences in the at% of P (p = 0.017) and zinc (Zn) (p = 0.010) between the demineralized and remineralized dentin. There was a significant difference in the at% of P (p = 0.030) between the demineralized and remineralized enamel. The Zn at% in enamel was significantly higher after remineralization in G5 as compared to the control group (p < 0.05). The images of the demineralized enamel showed the usual keyhole prism appearance, with intact prism sheaths and negligible inter-prism porosity.
The scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) findings seem to confirm the effectiveness of DentaSave Zinc for the remineralization of enamel lesions.
龋齿的发生是由于致龋微生物代谢可发酵碳水化合物释放有机酸。微生物、遗传、免疫、行为和环境因素在龋齿的发生和严重程度中发挥作用。
本研究旨在探讨不同漱口水对牙齿再矿化的可能影响。
本体外研究比较了局部应用于牙釉质表面的不同漱口水的再矿化能力。从颊侧和舌侧各制备 10 颗牙，共 50 颗牙标本，每组 10 颗牙：G1（对照组）；G2（李施德林®）；G3（舒适达®）；G4（Oral B® Pro-Expert）；G5（DentaSave®锌）。对所有组进行再矿化能力评估。采用单因素方差分析（ANOVA）和配对样本 t 检验进行统计学分析，p 值<0.05 认为差异有统计学意义。
脱矿牙本质和再矿化牙本质之间的钙（Ca）/磷（P）原子百分比（at%）比值存在显著差异（p = 0.001），脱矿牙釉质和再矿化牙釉质之间也存在显著差异（p = 0.006）。同样，脱矿牙本质中 P 的 at%（p = 0.017）和锌（Zn）的 at%（p = 0.010）与脱矿牙本质之间存在显著差异。脱矿牙釉质中 P 的 at%也存在显著差异（p = 0.030）。与对照组相比，G5 组牙釉质再矿化后 Zn 的 at%显著升高（p < 0.05）。脱矿牙釉质的 SEM 图像显示典型的牙本质关键孔棱柱体外观，完整的棱柱鞘和可忽略不计的棱柱间孔隙。
SEM 和能量色散 X 射线光谱（EDS）的结果似乎证实了 DentaSave 锌对牙釉质病变再矿化的有效性。
