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颅内毛细血管血管瘤的生长:一例报告。

Documented growth of an intracranial capillary hemangioma: A case report.

机构信息

Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.

出版信息

Neuropathology. 2024 Feb;44(1):76-82. doi: 10.1111/neup.12933. Epub 2023 Jul 4.

Abstract

Intracranial capillary hemangiomas in adults are rare, and diagnosis can be challenging. Hemangiomas, in general (and particularly in the skin), are more often noted in the pediatric population. Due to the lack of imaging undertaken in the presymptomatic phase, the literature provides few clues on the rate of growth of these unusual tumors. Therefore, we report a case of a 64-year-old man with a medical history of Lyme disease who presented with exhaustion and confusion. Imaging demonstrated an intra-axial lesion with vascularity in the posterior right temporal lobe, raising the possibility of a glioma. Imaging two years prior revealed a very small lesion in the same location. The patient underwent a craniectomy, total resection of the lesion was completed, and his symptoms of confusion resolved. Biopsy revealed a capillary hemangioma composed of small vascular channels lined by endothelial cells and pericytes without smooth muscle. Features of glioma, vascular neoplasms or neuroborreliosis (cerebral Lyme disease) were not identified. Our case documents the growth over two years of a rare intracranial capillary hemangioma in an older adult male.

摘要

成人颅内毛细血管血管瘤较为罕见,诊断具有一定挑战性。一般而言(尤其是在皮肤中),血管瘤更常见于儿科人群。由于在无症状期未进行影像学检查,因此文献中关于这些不常见肿瘤生长速度的信息很少。因此,我们报告了一例 64 岁男性病例,该患者有莱姆病病史,表现为乏力和意识模糊。影像学检查显示右颞叶后部有一个具有血管性的脑内病变,提示可能为神经胶质瘤。两年前的影像学检查显示同一部位有一个非常小的病变。患者接受了颅骨切除术,完成了病变的完全切除,其意识模糊症状得到缓解。活检显示一个毛细血管血管瘤,由内皮细胞和周细胞排列的小血管通道组成,没有平滑肌。没有发现神经胶质瘤、血管性肿瘤或神经莱姆病(大脑莱姆病)的特征。我们的病例记录了一个罕见的颅内毛细血管血管瘤在一名老年男性中两年的生长过程。

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