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经皮肿瘤消融治疗小肾肿瘤的技术和结果。

Techniques and outcomes of percutaneous tumour ablation for small renal masses.

机构信息

European Association of Urology (EAU) Young Academic Urologists (YAU) Renal Cancer Working Group, Arnhem, Netherlands.

Department of Urology, Pederzoli Hospital, Peschiera del Garda.

出版信息

Curr Opin Urol. 2023 Sep 1;33(5):360-366. doi: 10.1097/MOU.0000000000001110. Epub 2023 Jul 5.

Abstract

PURPOSE OF REVIEW

Small renal masses suspected to be malignant have little potential for metastasis and disease-related mortality. Surgery remains the standard care but represents overtreatment in many cases. Percutaneous ablative technique, especially thermal ablation has emerged as a valid alternative.

RECENT FINDINGS

The increased availability of cross-sectional imaging has led to a large number of incidentally detected small renal masses (SRMs), many of which are of low grade and exhibit indolent behaviour. Since 1996, ablative techniques such as cryoablation, radiofrequency ablation, and microwave ablation have gained widespread acceptance for treatment of SRMs in patients who are not surgical candidates. In this review article, we provide an overview of each of the commonly used percutaneous ablative treatments for SRMs and summarize the current literature regarding the advantages and disadvantages of each technique.

SUMMARY

Although partial nephrectomy (PN) represents the standard treatment of SRMs, Thermal ablation techniques have been increasingly used showing acceptable efficacy, low complication rate, and equivalent survival. Cryoablation seems to be superior to radiofrequency ablation in terms of local tumour control and retreatment rates. However, selection criteria for thermal ablation are still under refinement.

摘要

目的综述

怀疑为恶性的小肾肿瘤转移和疾病相关死亡率的可能性很小。手术仍然是标准治疗方法,但在许多情况下代表过度治疗。经皮消融技术,特别是热消融已成为一种有效的替代方法。

最近的发现

横断面成像的广泛应用导致大量偶然发现的小肾肿瘤(SRM),其中许多为低级别且表现为惰性行为。自 1996 年以来,冷冻消融、射频消融和微波消融等消融技术已广泛用于不能手术的患者的 SRM 治疗。在这篇综述文章中,我们概述了每种常用的经皮消融治疗 SRM 的方法,并总结了每种技术的优缺点的当前文献。

总结

虽然部分肾切除术(PN)是 SRM 的标准治疗方法,但热消融技术的应用越来越广泛,显示出可接受的疗效、低并发症发生率和等效的生存率。冷冻消融在局部肿瘤控制和再治疗率方面似乎优于射频消融。然而,热消融的选择标准仍在不断完善。

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