Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Rutgers-Princeton Center for Computational Cognitive Neuropsychiatry, Rutgers University, Newark, NJ, USA.
Nat Hum Behav. 2023 Oct;7(10):1667-1681. doi: 10.1038/s41562-023-01640-7. Epub 2023 Jul 6.
Although online samples have many advantages for psychiatric research, some potential pitfalls of this approach are not widely understood. Here we detail circumstances in which spurious correlations may arise between task behaviour and symptom scores. The problem arises because many psychiatric symptom surveys have asymmetric score distributions in the general population, meaning that careless responders on these surveys will show apparently elevated symptom levels. If these participants are similarly careless in their task performance, this may result in a spurious association between symptom scores and task behaviour. We demonstrate this pattern of results in two samples of participants recruited online (total N = 779) who performed one of two common cognitive tasks. False-positive rates for these spurious correlations increase with sample size, contrary to common assumptions. Excluding participants flagged for careless responding on surveys abolished the spurious correlations, but exclusion based on task performance alone was less effective.
虽然在线样本对于精神病学研究有很多优势,但这种方法的一些潜在陷阱并没有被广泛理解。在这里,我们详细说明了在哪些情况下,任务行为和症状评分之间可能会出现虚假相关。这个问题的出现是因为许多精神病症状调查在普通人群中的得分分布是不对称的,这意味着在这些调查中粗心的应答者会表现出明显升高的症状水平。如果这些参与者在任务表现上同样粗心,这可能导致症状评分和任务行为之间出现虚假关联。我们在两个在线招募的参与者样本(共 779 人)中演示了这种结果模式,他们执行了两个常见认知任务中的一个。与常见假设相反,这些虚假关联的假阳性率随着样本量的增加而增加。排除在调查中被标记为粗心应答的参与者可以消除虚假关联,但仅基于任务表现进行排除效果较差。