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巩膜缝合后房型人工晶状体植入术复发性巩膜炎后并发巩膜穿孔的特应性皮炎患者2例

Two Cases of Atopic Dermatitis Patients With Scleral Perforation After Recurrent Scleritis Induced by Scleral-Sutured Posterior Chamber Intraocular Lens Implantation.

作者信息

Minamoto Akira, Harada Yosuke, Hiyama Tomona, Ohara Hiromi, Kiuchi Yoshiaki

机构信息

Department of Ophthalmology, Hiroshima University, Hiroshima, JPN.

出版信息

Cureus. 2023 Jun 8;15(6):e40153. doi: 10.7759/cureus.40153. eCollection 2023 Jun.

Abstract

This report describes two cases of atopic dermatitis patients with scleral perforation after recurrent scleritis induced by suture exposure after scleral-sutured posterior chamber intraocular lens (PC-IOL) implantation. The first patient was a 41-year-old man (case 1), and the second was a 46-year-old man (case 2). Both had a history of atopic dermatitis and scleral-sutured intraocular lens (IOL) implantation. Scleritis recurred at the suture site after scleral-sutured IOL implantation in both patients. Although the scleritis was controlled by topical and/or systemic anti-inflammatory drugs, the sclera was perforated in both cases because of exposure of the suture knots (after seven years in case 1 and after 11 years in case 2). In case 1, the superotemporal IOL haptic was also exposed over the conjunctiva, and in case 2, the ciliary body was incarcerated in the scleral hole with deformation of the pupil superonasally. Considering that there were no signs of severe intraocular inflammation, surgical intervention was performed in both cases. In case 1, IOL repositioning was performed with oral prednisolone cover at a dosage of 15 mg/day, starting two weeks prior to the surgery. The steroid dosage was gradually tapered off until two months after the surgery. In case 2, the scleral patch underwent without IOL extraction, and no steroid or immunosuppression cover was administered. There was no recurrence of scleritis after surgery in either case, and visual acuity was preserved in both cases. The scleral perforation that occurred after scleral-sutured IOL implantation in these patients was thought to be the result of recurrent scleritis caused by suture exposure and chronic mechanical irritation by a suture knot. The scleritis subsided without removal of the IOL by moving the suture site of the IOL haptic and covering the suture with a scleral flap or patch graft.

摘要

本报告描述了两例人工晶状体植入术后因缝线暴露导致复发性巩膜炎,进而引发巩膜穿孔的特应性皮炎患者。首例患者为一名41岁男性(病例1),第二例为一名46岁男性(病例2)。两人均有特应性皮炎病史及巩膜缝合人工晶状体(IOL)植入史。两例患者在巩膜缝合IOL植入术后,缝线部位均出现复发性巩膜炎。尽管巩膜炎通过局部和/或全身抗炎药物得到控制,但由于缝线结暴露(病例1为7年后,病例2为11年后),两例均发生了巩膜穿孔。在病例1中,颞上象限的IOL襻也暴露于结膜上方,在病例2中,睫状体嵌顿于巩膜孔内,瞳孔鼻上方变形。考虑到无严重眼内炎迹象,两例均进行了手术干预。在病例1中,在手术前两周开始口服泼尼松龙,剂量为15mg/天,进行IOL复位。类固醇剂量逐渐递减,直至术后两个月。在病例2中,进行了巩膜修补,未取出IOL,未给予类固醇或免疫抑制治疗。两例术后均未复发巩膜炎,视力均得以保留。这些患者在巩膜缝合IOL植入术后发生的巩膜穿孔被认为是缝线暴露导致复发性巩膜炎以及缝线结慢性机械刺激的结果。通过移动IOL襻的缝线部位并用巩膜瓣或补片移植覆盖缝线,巩膜炎在未取出IOL的情况下消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30bd/10329562/c0844ce264ce/cureus-0015-00000040153-i01.jpg

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