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基于深度学习的用于实体生物力学的患者特定心脏几何建模。

Patient-Specific Heart Geometry Modeling for Solid Biomechanics Using Deep Learning.

出版信息

IEEE Trans Med Imaging. 2024 Jan;43(1):203-215. doi: 10.1109/TMI.2023.3294128. Epub 2024 Jan 2.

DOI:10.1109/TMI.2023.3294128
PMID:37432807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10764002/
Abstract

Automated volumetric meshing of patient-specific heart geometry can help expedite various biomechanics studies, such as post-intervention stress estimation. Prior meshing techniques often neglect important modeling characteristics for successful downstream analyses, especially for thin structures like the valve leaflets. In this work, we present DeepCarve (Deep Cardiac Volumetric Mesh): a novel deformation-based deep learning method that automatically generates patient-specific volumetric meshes with high spatial accuracy and element quality. The main novelty in our method is the use of minimally sufficient surface mesh labels for precise spatial accuracy and the simultaneous optimization of isotropic and anisotropic deformation energies for volumetric mesh quality. Mesh generation takes only 0.13 seconds/scan during inference, and each mesh can be directly used for finite element analyses without any manual post-processing. Calcification meshes can also be subsequently incorporated for increased simulation accuracy. Numerous stent deployment simulations validate the viability of our approach for large-batch analyses. Our code is available at https://github.com/danpak94/Deep-Cardiac-Volumetric-Mesh.

摘要

患者特定心脏几何形状的自动容积网格划分有助于加速各种生物力学研究,例如介入后的应力估计。先前的网格划分技术通常忽略了成功进行下游分析的重要建模特征,特别是对于瓣膜等薄结构。在这项工作中,我们提出了 DeepCarve(深心机 脏容积网格划分):一种新颖的基于变形的深度学习方法,可自动生成具有高精度空间和高质量元素的患者特定容积网格。我们方法的主要新颖之处在于使用最小充分的表面网格标签来实现精确的空间精度,以及同时优化各向同性和各向异性变形能以提高体积网格质量。在推断过程中,网格生成仅需 0.13 秒/次扫描,并且每个网格都可以直接用于有限元分析,无需任何手动后处理。随后还可以合并钙化网格以提高模拟精度。大量支架部署模拟验证了我们的方法在大规模分析中的可行性。我们的代码可在 https://github.com/danpak94/Deep-Cardiac-Volumetric-Mesh 上获得。

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2
Automatic Aortic Valve Cusps Segmentation from CT Images Based on the Cascading Multiple Deep Neural Networks.基于级联多个深度神经网络的CT图像自动主动脉瓣尖分割
J Imaging. 2022 Jan 14;8(1):11. doi: 10.3390/jimaging8010011.
3
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4
The Impact of Self-Expandable Transcatheter Aortic Valve Replacement on Concomitant Functional Mitral Regurgitation: A Comprehensive Engineering Analysis.自膨胀经导管主动脉瓣置换术对合并功能性二尖瓣反流的影响:一项全面的工程分析
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STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement.经导管主动脉瓣置换术的STS-ACC TVT注册研究
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