钙通透性AMPA受体：治疗脑部疾病时被低估的药理学靶点。 - Suppr

Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies.

作者信息

Gaidin Sergei G, Kosenkov Artem M

机构信息

Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.

出版信息

Neural Regen Res. 2023 Dec;18(12):2669-2670. doi: 10.4103/1673-5374.373714.

DOI:10.4103/1673-5374.373714

PMID:37449615

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10358676/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/10358676/0259b3d87a67/NRR-18-2669-g001.jpg

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Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies.

作者信息

Gaidin Sergei G, Kosenkov Artem M

机构信息

Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.

出版信息

Neural Regen Res. 2023 Dec;18(12):2669-2670. doi: 10.4103/1673-5374.373714.

DOI:10.4103/1673-5374.373714

PMID:37449615

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10358676/

Abstract

摘要

相似文献

Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies.

Neural Regen Res. 2023 Dec;18(12):2669-2670. doi: 10.4103/1673-5374.373714.

Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5.

J Physiol. 2016 Feb 15;594(4):837-61. doi: 10.1113/JP271394. Epub 2015 Dec 17.

Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord.

J Pharmacol Exp Ther. 2019 Nov;371(2):242-249. doi: 10.1124/jpet.119.261339. Epub 2019 Sep 3.

Developing rat brainstem motoneurones in organotypic culture express calcium permeable AMPA-gated receptors.

Brain Res. 1998 Jan 19;781(1-2):148-58. doi: 10.1016/s0006-8993(97)01225-0.

Subpopulations of GABAergic and non-GABAergic rat dorsal horn neurons express Ca2+-permeable AMPA receptors.

Eur J Neurosci. 1999 Aug;11(8):2758-66. doi: 10.1046/j.1460-9568.1999.00691.x.

Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus.

J Neurosci. 2016 Jan 13;36(2):622-31. doi: 10.1523/JNEUROSCI.3625-15.2016.

Calcium permeable AMPA receptors and autoreceptors in external tufted cells of rat olfactory bulb.

Neuroscience. 2007 Feb 9;144(3):1094-108. doi: 10.1016/j.neuroscience.2006.10.041. Epub 2006 Dec 6.

AMPA receptors in epilepsy and as targets for antiepileptic drugs.

Adv Neurol. 1999;79:947-63.

Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes.

Neuropharmacology. 2015 Dec;99:396-407. doi: 10.1016/j.neuropharm.2015.08.011. Epub 2015 Aug 7.

Blocking effect of 1-naphthyl acetyl spermine on Ca(2+)-permeable AMPA receptors in cultured rat hippocampal neurons.

Neurosci Res. 1997 Sep;29(1):27-36. doi: 10.1016/s0168-0102(97)00067-9.

引用本文的文献

Identification of Neurons Containing Calcium-Permeable AMPA and Kainate Receptors Using Ca Imaging.

Bio Protoc. 2025 Feb 5;15(3):e5199. doi: 10.21769/BioProtoc.5199.

Astrocyte Regulation of Neuronal Function and Survival in Stroke Pathophysiology.

Adv Neurobiol. 2024;39:233-267. doi: 10.1007/978-3-031-64839-7_10.

Gene Expression at the Tripartite Synapse: Bridging the Gap Between Neurons and Astrocytes.

Adv Neurobiol. 2024;39:95-136. doi: 10.1007/978-3-031-64839-7_5.

Antiepileptic profile of Parawixin-11, purified from Parawixia bistriata spider venom (Araneae, Araneidae), in Wistar rats.

Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):629-639. doi: 10.1007/s00210-024-03299-x. Epub 2024 Jul 23.

Nano-organization of synaptic calcium signaling.

Biochem Soc Trans. 2024 Jun 26;52(3):1459-1471. doi: 10.1042/BST20231385.

本文引用的文献

A novel approach for vital visualization and studying of neurons containing Ca -permeable AMPA receptors.

J Neurochem. 2023 Mar;164(5):583-597. doi: 10.1111/jnc.15729. Epub 2022 Dec 7.

Calcium Permeable-AMPA Receptors and Excitotoxicity in Neurological Disorders.

Front Neural Circuits. 2021 Aug 17;15:711564. doi: 10.3389/fncir.2021.711564. eCollection 2021.

Potential mechanism of GABA secretion in response to the activation of GluK1-containing kainate receptors.

Neurosci Res. 2021 Oct;171:27-33. doi: 10.1016/j.neures.2021.03.009. Epub 2021 Mar 27.

Ca -permeable AMPA receptors and their auxiliary subunits in synaptic plasticity and disease.

J Physiol. 2021 May;599(10):2655-2671. doi: 10.1113/JP279029. Epub 2021 Feb 21.

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking.

Cell Mol Life Sci. 2019 Jun;76(11):2133-2169. doi: 10.1007/s00018-019-03068-7. Epub 2019 Apr 1.

Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.

Neuron. 2018 Sep 5;99(5):956-968.e4. doi: 10.1016/j.neuron.2018.07.027. Epub 2018 Aug 16.

Selective vulnerability of hippocampal interneurons to graded traumatic brain injury.

Neurobiol Dis. 2019 Sep;129:208-216. doi: 10.1016/j.nbd.2018.07.022. Epub 2018 Jul 19.

Hippocampal GABAergic Inhibitory Interneurons.

Physiol Rev. 2017 Oct 1;97(4):1619-1747. doi: 10.1152/physrev.00007.2017.

Endocytosis and lysosomal degradation of GluA2/3 AMPARs in response to oxygen/glucose deprivation in hippocampal but not cortical neurons.

Sci Rep. 2017 Sep 26;7(1):12318. doi: 10.1038/s41598-017-12534-w.

The vulnerability of calretinin-containing hippocampal interneurons to temporal lobe epilepsy.

Front Neuroanat. 2014 Sep 29;8:100. doi: 10.3389/fnana.2014.00100. eCollection 2014.

Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies.

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Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies.

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