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因罪犯病变接受经皮冠状动脉介入治疗的ST段抬高型心肌梗死患者冠状动脉分叉处—— jailed半充盈球囊的疗效和安全性

STEMI patients receiving percutaneous coronary intervention for a culprit lesion with coronary artery bifurcation-efficacy and safety of the jailed semi-inflated balloon.

作者信息

Lin Tzu-Hsiang, Chen Kuan-Ju, Hu Yu-Cheng, Chang Keng-Hao, Lai Chih-Hung, Liu Tsun-Jui, Lee Wen-Lieng, Su Chieh-Shou

机构信息

Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.

Department of Emergency Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

出版信息

Front Cardiovasc Med. 2023 Jun 30;10:1132062. doi: 10.3389/fcvm.2023.1132062. eCollection 2023.

Abstract

BACKGROUND

We aimed to evaluate the efficacy and safety of the 'jailed semi-inflated balloon technique' (JSIBT) for side branch (SB) protection in STEMI patients with a culprit lesion involving a coronary artery bifurcation while undergoing emergent percutaneous coronary intervention (PCI).

METHODS

We treated between Jan, 2011 and Jun, 2020, a total of 264 STEMI patients with a culprit lesion that involved a coronary artery bifurcation using primary PCI. In 30 patients, SB was protected by JSIBT (the JSIBT group). In 234 patients, SB was either protected or not protected by a placed wire (the non-JSIBT group).

RESULTS

In both groups, after PCI procedure, TIMI flows of main vessel (MV) and SB were increased significantly compared with their measurements before the procedure. TIMI flows of post-procedural MV were similar between the two groups. In the JSIBT group, TIMI flows of SB both peri-procedure and post-procedure measurements were significantly greater than the non-JSIBT group. Despite a higher incidence of SB dissection in the JSIBT group, no inter-group difference was found in their total SB complications (like SB dissection, SB occlusion, wire entrapment or balloon rupture/entrapment). While JSIBT was an independent predictor for the SB TIMI 3 flow measured at the end of primary PCI, it was not an independent predictor for SB complications.

CONCLUSION

The use of JSIBT as a method of SB protection during primary PCI not only provided better SB protection, but it also had a similar rate of SB complications compared with those with or without prior application of SB wire. This technique may be an effective method of protecting SB for STEMI patients involving coronary artery bifurcation and underwent emergent PCI.

摘要

背景

我们旨在评估“ jailed半充盈球囊技术”(JSIBT)在急性ST段抬高型心肌梗死(STEMI)患者中,对罪犯病变累及冠状动脉分叉处进行急诊经皮冠状动脉介入治疗(PCI)时,对边支(SB)的保护效果及安全性。

方法

2011年1月至2020年6月,我们共对264例罪犯病变累及冠状动脉分叉处的STEMI患者进行了直接PCI治疗。其中30例患者采用JSIBT保护边支(JSIBT组)。234例患者边支由置入导丝保护或未保护(非JSIBT组)。

结果

两组患者PCI术后,主支血管(MV)和边支的心肌梗死溶栓试验(TIMI)血流较术前均显著增加。两组术后MV的TIMI血流相似。JSIBT组围手术期及术后边支的TIMI血流均显著高于非JSIBT组。尽管JSIBT组边支夹层发生率较高,但两组边支总并发症(如边支夹层、边支闭塞、导丝嵌顿或球囊破裂/嵌顿)无差异。虽然JSIBT是直接PCI结束时边支TIMI 3级血流的独立预测因素,但不是边支并发症的独立预测因素。

结论

在直接PCI中使用JSIBT作为边支保护方法,不仅能提供更好的边支保护,而且与使用或未使用边支导丝的患者相比,边支并发症发生率相似。该技术可能是保护罪犯病变累及冠状动脉分叉处并接受急诊PCI的STEMI患者边支的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eed/10349388/f82682a456d2/fcvm-10-1132062-g001.jpg

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