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兔大肠肌间神经丛分布的定量分析

Quantitative analysis of the distribution of the myenteric plexus in the rabbit large intestine.

作者信息

Kigata Tetsuhito, Koyama Tatsuhiro, Lu Xizi, Shibata Hideshi

机构信息

Department of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, Japan.

Laboratory of Veterinary Anatomy, Faculty and Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Japan.

出版信息

Anat Histol Embryol. 2023 Nov;52(6):1029-1033. doi: 10.1111/ahe.12950. Epub 2023 Jul 17.

Abstract

Rabbit large intestine has a segment-specific morphology and motility. However, the morphological features of the myenteric plexus, which controls intestinal motility, have not been characterized in each large intestinal segment. We investigated the myenteric plexus morphology in the rabbit large intestine using protein gene product 9.5 immunohistochemistry in whole-mount preparations. The tenial part of the first and second segments of the proximal colon had the most well developed myenteric plexus, while the caecum had the least. These findings suggest different neuronal control over the motility of each intestinal segment, thereby providing a fundamental understanding of the rabbit enteric nervous system.

摘要

兔的大肠具有节段特异性形态和运动性。然而,控制肠道运动的肌间神经丛的形态特征在大肠的各个节段中尚未得到描述。我们使用全层标本中的蛋白基因产物9.5免疫组织化学方法,研究了兔大肠中肌间神经丛的形态。近端结肠第一和第二段的带部肌间神经丛发育最为完善,而盲肠的则最不发达。这些发现提示对每个肠段运动的神经元控制存在差异,从而为兔肠道神经系统提供了基本认识。

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