School of Biological Science & Medical Engineering, Southeast University, Nanjing, China.
Nanovision Technology (Beijing) Co.,Ltd., Beijing, China.
Med Phys. 2024 Jan;51(1):251-266. doi: 10.1002/mp.16639. Epub 2023 Jul 19.
Improving imaging speed has always been the focus of research in CT technology, which is related to the radiation dose and imaging quality of moving organs, including heart and blood vessels. However, it is difficult to achieve further improvement by increasing the rotation speed of the gantry due to its structural strength limitation. Differing from the conventional CTs, the static CT employs dozens of ray sources to acquire projection data from different angular ranges, and each source only needs to be rotated in a small range to finish a full 360° scan, thus greatly increasing the scanning speed.
As sources of static CT need to be evenly distributed over 360°, the sources and detectors have to be arranged on two parallel rings independently. Such a geometry can be considered as a special case of CT systems with a significantly large cone angle, that is, a part of the detector is missing in the vicinity of the mid-plane. Due to restriction of upper and lower bounds of the cone angle of the static CT, there are uneven projection data varying in each portion of the reconstruction volume, the conventional analytical or iterative reconstruction methods may introduce artifacts in the reconstructed outcomes.
Following the weighting approach extended FDK (xFDK) by Grimmer et al., we propose an improved bilateral xFDK algorithm (bixFDK), which focuses on the reconstruction of the expanded volume. With the same philosophy as xFDK in terms of weighting function design, bixFDK takes the longitudinal offset of the detector with respect to the source into consideration, making our method applicable to a wide range of CT geometries, especially for the static CT. Based on the proposed bixFDK, a new iterative scheme bixFDK-IR is also constructed to extend the applications to a wide range of scan protocols such as sparse-view scan.
The proposed method has been validated with the simulated phantom data and the actual clinical data of the static CT, and demonstrates that it can ensure good image quality and enlarge the reconstruction volume in z-direction of the static CT.
The bixFDK algorithm is an ideal reconstruction approach for static CT geometry, and the iterative scheme of bixFDK-IR is applicable to a wide range of CT geometries and scan protocols, thus providing a wide range of application scenarios.
提高成像速度一直是 CT 技术研究的重点,这与心脏和血管等运动器官的辐射剂量和成像质量有关。然而,由于其结构强度的限制,通过增加机架的旋转速度很难进一步提高。与传统 CT 不同,静态 CT 使用数十个射线源从不同的角度范围获取投影数据,每个射线源只需在小范围内旋转即可完成完整的 360°扫描,从而大大提高了扫描速度。
由于静态 CT 的射线源需要均匀分布在 360°,因此射线源和探测器必须独立地安装在两个平行的圆环上。这种几何形状可以被认为是具有显著大锥角的 CT 系统的特殊情况,即在中平面附近缺少一部分探测器。由于静态 CT 的锥角上下限的限制,重建体的各个部分的投影数据不均匀,传统的解析或迭代重建方法可能会在重建结果中引入伪影。
在 Grimmer 等人扩展的 FDK(xFDK)加权方法的基础上,我们提出了一种改进的双边 xFDK 算法(bixFDK),该算法专注于扩展体积的重建。与 xFDK 在加权函数设计方面的理念相同,bixFDK 考虑了探测器相对于射线源的纵向偏移,使我们的方法适用于广泛的 CT 几何形状,特别是静态 CT。基于提出的 bixFDK,还构建了一种新的迭代方案 bixFDK-IR,以将应用扩展到广泛的扫描协议,如稀疏视图扫描。
该方法已通过静态 CT 的模拟体模数据和实际临床数据进行了验证,结果表明,它可以保证良好的图像质量并扩大静态 CT 的 z 方向的重建体积。
bixFDK 算法是静态 CT 几何形状的理想重建方法,bixFDK-IR 的迭代方案适用于广泛的 CT 几何形状和扫描协议,从而提供了广泛的应用场景。