Chen Wei, Yokoyama Minato, Waseda Yuma, Kobayashi Masaki, Fan Bo, Fukuda Shohei, Tanaka Hajime, Yoshida Soichiro, Ai Masumi, Fushimi Kiyohide, Fujii Yasuhisa
Department of Urology, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Insured Medical Care Management, Tokyo Medical and Dental University, Tokyo, Japan.
Int J Urol. 2023 Nov;30(11):1014-1019. doi: 10.1111/iju.15250. Epub 2023 Jul 20.
To evaluate the surgical outcomes of robot-assisted radical cystectomy (RARC) in octogenarian or older patients based on a Japanese nationwide database.
The diagnosis procedure combination database was used to extract the data on radical cystectomy cases. Surgical outcomes of RARC in octogenarian or older patients (older group) were initially compared to those of patients younger than 80 years (younger group). Then, the surgical outcomes of RARC in the older group were compared to those of open radical cystectomy (ORC) and laparoscopic radical cystectomy (LRC) in the same age group.
Between 2018 and 2021, 478 RARC cases in the older group and 2257 RARC cases in the younger group were identified. In the older group, ileal conduit, neobladder, and other urinary diversions were carried out in 352 (73.6%), 22 (4.6%), and 104 (21.8%) patients, respectively. In the older group, when compared with the younger group, the complication rate (24.9%), blood transfusion rate (41.4%), and in-hospital mortality (1.4%) were equivalent, while significantly shorter anesthesia time and longer length of stay were observed in the older group (521.0 ± 140.4 min vs. 595.1 ± 141.71 min, p < 0.01, and 32.9 ± 16.8 days vs. 30.6 ± 17.8 days, p = 0.01, respectively). In the comparison of the surgical outcomes of older patients receiving RARC to those receiving ORC (n = 746) and LRC (n = 375), the RARC group had the lowest complication rate and the shortest length of stay, while the shortest anesthesia time was noted in the ORC group.
The feasibility of RARC for octogenarian or older patients was demonstrated by the nationwide database study.
基于日本全国性数据库评估机器人辅助根治性膀胱切除术(RARC)在80岁及以上患者中的手术效果。
使用诊断程序组合数据库提取根治性膀胱切除术病例的数据。首先将80岁及以上患者(老年组)的RARC手术效果与80岁以下患者(年轻组)的进行比较。然后,将老年组中RARC的手术效果与同年龄组的开放性根治性膀胱切除术(ORC)和腹腔镜根治性膀胱切除术(LRC)的进行比较。
在2018年至2021年期间,确定了老年组478例RARC病例和年轻组2257例RARC病例。在老年组中,分别有352例(73.6%)、22例(4.6%)和104例(21.8%)患者进行了回肠膀胱术、新膀胱术和其他尿流改道术。在老年组中,与年轻组相比,并发症发生率(24.9%)、输血率(41.4%)和住院死亡率(1.4%)相当,而老年组的麻醉时间明显更短,住院时间更长(分别为521.0±140.4分钟对595.1±141.71分钟,p<0.01;32.9±16.8天对30.6±17.8天,p=0.01)。在接受RARC的老年患者与接受ORC(n=746)和LRC(n=375)的老年患者的手术效果比较中,RARC组的并发症发生率最低,住院时间最短,而ORC组的麻醉时间最短。
全国性数据库研究证明了RARC在80岁及以上患者中的可行性。