Chung Chong Hyuk, Jang Gyuho, Lee Chang-Hoon
Division of Rheumatology, Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.
J Rheum Dis. 2021 Jan 1;28(1):31-37. doi: 10.4078/jrd.2021.28.1.31.
Fibromyalgia (FM) is a disorder characterized by chronic diffuse pain and enhanced pain response to stimuli and is caused by central sensitization Tinnitus also is related to central sensitization So we investigated the impact of tinnitus on FM.
We included 22 FM patients with tinnitus and 25 FM patients without tinnitus We assessed a range of symptoms using the Widespread Pain Index; Symptom Severity Score scale; Visual Analogue Scale of pain; and the Korean versions of the Fibromyalgia Impact Questionnaire (FIQ), the Insomnia Severity Index, and the Short-form Health Survey (SF-36) Information about the severity of tinnitus in FM patients was evaluated using the Korean version of the Tinnitus Handicap Questionnaire (THQ-K).
There were significant differences between the group that had mild tinnitus (THQ<38) and the group that had moderate-to-severe tinnitus (THQ≥38) for FIQ score (p=0025) and for the physical functioning (p=0003), social functioning (p=0035), and mental health (p=0017) components of the SF-36 Also, after dividing patients into 2 groups according to insomnia severity, significant differences were observed in FIQ score (p=0002) and in body pain (p=0001), general health (p=0008), vitality (p=0003), social functioning (p=0003), role limitation due to emotional condition (p=0001), and mental health (p<0001) components of the SF-36.
The FM patients with severe tinnitus had more functional impairments and lower quality of life than those with mild tinnitus Severe insomnia also was accompanied by worse health status and lower quality of life.
纤维肌痛(FM)是一种以慢性弥漫性疼痛和对刺激的疼痛反应增强为特征的疾病,由中枢敏化引起。耳鸣也与中枢敏化有关。因此,我们研究了耳鸣对纤维肌痛的影响。
我们纳入了22名伴有耳鸣的纤维肌痛患者和25名不伴有耳鸣的纤维肌痛患者。我们使用广泛性疼痛指数、症状严重程度评分量表、疼痛视觉模拟量表以及纤维肌痛影响问卷(FIQ)、失眠严重程度指数和简短健康调查问卷(SF-36)的韩文版评估了一系列症状。使用耳鸣 handicap问卷韩文版(THQ-K)评估纤维肌痛患者耳鸣的严重程度信息。
轻度耳鸣组(THQ<38)和中度至重度耳鸣组(THQ≥38)在FIQ评分(p=0.025)以及SF-36的身体功能(p=0.003)、社会功能(p=0.035)和心理健康(p=0.017)分量表方面存在显著差异。此外,根据失眠严重程度将患者分为两组后,在FIQ评分(p=0.002)以及SF-36的身体疼痛(p=0.001)、总体健康(p=0.008)、活力(p=0.003)、社会功能(p=0.003)、因情绪状况导致的角色受限(p=0.001)和心理健康(p<0.001)分量表方面观察到显著差异。
与轻度耳鸣的纤维肌痛患者相比,重度耳鸣的纤维肌痛患者功能障碍更多,生活质量更低。严重失眠也伴随着更差的健康状况和更低的生活质量。