Department of Chemistry, Dartmouth College, Hanover, NH, 03755, USA.
Prog Chem Org Nat Prod. 2023;121:1-546. doi: 10.1007/978-3-031-26629-4_1.
The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number-from fewer than 25 in 1968-to approximately 8000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.
本卷是三卷本系列的第三卷，记录了天然存在的有机卤化合物，使总数从 1968 年的不到 25 个增加到目前的约 8000 个化合物。几乎所有这些天然产物都含有氯或溴，少数含有碘，更少的含有氟。这些有机卤化物由无处不在的海洋（藻类、海绵、珊瑚、苔藓动物、裸鳃类动物、真菌、细菌）和陆地生物（植物、真菌、细菌、昆虫、高等动物）以及普遍的非生物过程（火山、森林火灾、地热事件）产生，遍布全球生态系统。新发现的外星来源也有记录。除了化学结构外，还介绍了生物活性、生物卤化、生物降解、自然功能和未来展望。
