Cambridge University Hospitals NHS Foundation Trust, UK.
University of Cambridge, UK.
Ann R Coll Surg Engl. 2023 Nov;105(8):781-785. doi: 10.1308/rcsann.2023.0050. Epub 2023 Jul 25.
Stromal tumour of uncertain malignant potential (STUMP) is a rare tumour of the prostate with variable and unpredictable risk and clinical progression. There is no clear consensus on how it should be managed. We describe two cases of patients who presented to their general practitioners with raised prostate-specific antigen in one instance and an abnormal digital rectal examination in the other. Biopsies were carried out and a diagnosis of STUMP was made. Both cases were managed with robot-assisted radical prostatectomy and after 4.8 years of follow-up, there has not been any recurrence. This is the first reported UK case in which STUMP has been successfully managed with robotic surgery with excellent medium-term results. Radical prostatectomy can be used to treat STUMP tumour with good oncological and functional outcomes.
交界性前列腺基质肿瘤(STUMP)是一种罕见的前列腺肿瘤,其风险和临床进展具有变异性和不可预测性。目前对于如何处理这种肿瘤尚无明确共识。我们描述了两例患者的情况,一例患者因前列腺特异性抗原升高,另一例患者因直肠指检异常而就诊于全科医生。进行了活检,诊断为 STUMP。两例均采用机器人辅助根治性前列腺切除术治疗,随访 4.8 年后均未复发。这是首例在英国成功采用机器人手术治疗 STUMP 的病例,中期结果良好。根治性前列腺切除术可用于治疗 STUMP 肿瘤,具有良好的肿瘤学和功能学结果。