中尺度序列特征在抗体多样化过程中调节激活诱导胞嘧啶脱氨酶（AID）的活性。 - Suppr

Mesoscale sequence feature modulates AID activity in antibody diversification.

作者信息

Li Jiayang, Dai Hai-Qiang

出版信息

Acta Biochim Biophys Sin (Shanghai). 2023 Aug 3;55(9):1515-1517. doi: 10.3724/abbs.2023145.

DOI:10.3724/abbs.2023145

PMID:37537958

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10520465/

Abstract

摘要

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Mesoscale sequence feature modulates AID activity in antibody diversification.

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本文引用的文献

Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation.

Cell. 2023 May 11;186(10):2193-2207.e19. doi: 10.1016/j.cell.2023.03.030. Epub 2023 Apr 24.

AID function in somatic hypermutation and class switch recombination.

Acta Biochim Biophys Sin (Shanghai). 2022 May 25;54(6):759-766. doi: 10.3724/abbs.2022070.

Cis- and trans-factors affecting AID targeting and mutagenic outcomes in antibody diversification.

Adv Immunol. 2019;141:51-103. doi: 10.1016/bs.ai.2019.01.002. Epub 2019 Feb 11.

AID Recognizes Structured DNA for Class Switch Recombination.

Mol Cell. 2017 Aug 3;67(3):361-373.e4. doi: 10.1016/j.molcel.2017.06.034. Epub 2017 Jul 27.

Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes.

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Mesoscale sequence feature modulates AID activity in antibody diversification.

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