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截瘫作为复发急性髓系白血病的罕见临床表现

Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia.

作者信息

Osman Haitham, Gism Elseed Israa, Hussein Sheikheldein B, Mando Naima, Alraheili Alaa A

机构信息

Hematology, Prince Muhammad Bin Abdulaziz Hospital, Ministry of National Guard Health Affairs, Madinah, SAU.

Medicine, Prince Muhammad Bin Abdulaziz Hospital, Ministry of National Guard Health Affairs, Madinah, SAU.

出版信息

Cureus. 2023 Jul 5;15(7):e41421. doi: 10.7759/cureus.41421. eCollection 2023 Jul.

Abstract

Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as acute flaccid paraplegia with a certain sensory level. On thoracic spine magnetic resonance imaging (MRI), an epidural mass compressing the spinal cord at the level of the thoracic spine segment 4 (T4) was found. The mass histology confirmed the diagnosis of myeloid sarcoma.

摘要

髓系肉瘤,也称为粒细胞肉瘤或绿色瘤,是恶性髓系母细胞的髓外积聚,导致实体瘤形成。在此,我们报告一例急性髓系白血病(AML)的罕见表现,其疾病复发在临床上表现为急性弛缓性截瘫并伴有一定的感觉平面。在胸椎磁共振成像(MRI)上,发现一个硬膜外肿块在胸椎第4节段(T4)水平压迫脊髓。肿块组织学检查确诊为髓系肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9325/10403294/2eb1d7f179e1/cureus-0015-00000041421-i01.jpg

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